Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 87 for “"Langerhans"”.
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Characterization of human foreskin Langerhans cells
… HIV target cells such as CD4+ macrophages, T, Langerhans (LCs), and dendritic cells (DCs). However, there have been different reports on whether the inner FS or outer FS has more HIV target cells. While LCs have been implicated in HIV transmission, their role remains controversial. Studies have …
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Dynamic Behaviors of Langerhans Cells In Situ
… are protected by an array of immune cells called Langerhans cells (LCs). As a bridge between the innate (non-specific) and adaptive (specific) immune responses, LCs sense injurious stimuli and contribute to tissue inflammation as well as initiate the antibody- or cell-mediated specific responses …
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Defining interactions between Mycobacterium leprae and Langerhans cells
… immune cells like dendritic cells, specifically Langerhans cells, have not been studied as extensively. The findings that M. leprae antigens can be presented via CD1a on Langerhans cells has spurred interest in understanding how Langerhans cells interact and uptake M. leprae leading to downstream …
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Insulin-secreting tumors of the islets of Langerhans
Thesis (M.D.)—-Boston University
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Σύγχρονα δεδομένα για τη διάγνωση και θεραπεία της ιστιοκύττωσης Langerhans / Current concepts for the diagnosis and management of Langerhans cell histiocytosis
Η ιστιοκύττωση Langerhans αποτελεί σπάνια ιστιοκυτταρική διαταραχή με ιδιαίτερα ετερογενή κλινική εικόνα, η οποία μπορεί να κυμαίνεται από εντοπισμένη, αυτοϊώμενη νόσο έως πολυσυστηματική μορφή με σοβαρή νοσηρότητα και αυξημένη θνητότητα. Η νόσος χαρακτηρίζεται από κλωνικό πολλαπλασιασμό …
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Investigating lesions of Langerhans cells and their role in Lymphoproliferative diseases
Langerhan’s cells (LCs) are the immune sentinels of the skin, sampling the cutaneous microenvironment and presenting captured antigen to T cells. A sheet-like proliferation of LCs is termed Langerhan’s cell histiocytosis (LCH), an enigmatic and poorly understood disorder with a widely varied …
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Untersuchungen zur Isolierung, Reinigung und In-Vitro-Funktion porziner Langerhans-Inseln
… Reinigung und In-Vitro-Funktion porziner Langerhans-Inseln
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Development of quantitative methods for quality assessment of islets of Langerhans
Transplantation of isolated islets of Langerhans has promising potential to cure type 1 diabetes by inducing long-term normoglycemia and insulin independence. The feasibility of clinical islet transplantations has been established according to the Edmonton Protocol. However, results are variable, …
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Etablierung des Modells "Ratte-anti-Schwein" zur xenogenen Transplantation mikroverkapselter Langerhans-Inseln
… zur xenogenen Transplantation mikroverkapselter Langerhans-Inseln. Funktionelle und histologische Analysen geben Auskunft über das Schicksal der Inselzell-Transplantate in den diabetischen Ratten. Isolierung, Kultivierung und die Mikroverkapselung der porzinen Langerhans-Inseln mit hochreinen …
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ΣΥΜΒΟΛΗ ΣΤΗ ΜΕΛΕΤΗ ΤΩΝ ΚΥΤΤΑΡΩΝ LANGERHANS ΣΤΗΝ ΕΠΟΥΛΩΣΗ ΤΡΑΥΜΑΤΟΣ. ΠΕΙΡΑΜΑΤΙΚΗ ΜΕΛΕΤΗ ΣΕ ΛΕΥΚΟΥΣ ΕΠΙΜΥΣ
LANGERHANS CELLS ARE EPIDERMAL CELLS AND WERE DESCRIBED BY P. LANGERHANS IN 1868. FOR SOME TIME AFTER THEIR DISCOVERY, THEIR ORIGIN, NATURE AND FUNCTIONS REMAINED UNKNOWN. THE AIM OF THIS STUDY WAS TO DETERMINE (1) THE QUANTITATIVE DISTRIBUTION OF LANGERHANS CELLS DURING THE HEALING PROCESS OF …
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Untersuchungen zur humoralen Immunantwort in Wistar-Ratten nach xenogener Transplantation mikroverkapselter Langerhans-Inseln des Schweins
… Transplantation von mikroverkapselten porzinen langerhans-Inseln ist ein attraktives Konzept, um zukünftig Typ I Diabetiker zu therapieren. Unklar ist jedoch, ob die zur Immunisolation verwendeten Alginat-Mikrokapseln die humorale Immunantwort gegen die porzinen Inselzellen hemmen oder sogar …
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Τα κύτταρα Langerhans στο ακανθοκυτταρικό καρκίνωμα του στόματος: ανοσοϊστοχημική μελέτη με την S-100 πρωτεΐνη
… ORAL SQUAMUS CELL CARCINOMA FOR THE PRESENCE OF LANGERHANS CELLS (L.C) IN FORMALIN-FIXED, PARAFIN-EMBEDED MATERIAL, BY USING S-100 PROTEIN IN THE INDIRECT IMMUNOPEROXIDASE METHOD. ITWAS FOUND THAT: 1) S-100 PROTEIN IS A GOOD MARKER FOR THE IMMUNOHISTOCHEMICAL IDENTIFICATION OF L.C IN ORAL SQUAMUS …
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A Study of Glucose Stimulus Insulin Secretion Coupling using Lean and Obese Mouse Islets of Langerhans
… has been investigated using isolated islets of Langerhans from lean homozygous (+/+) and genetically obese hyperglycaemic (ob/ob) mice. Streptozotocin inhibition of the insulin response to glucose but not glucagon suggests glucose sensitive sites and adenylate cyclase systems to be separate …
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Deficiência de arginina-vasopressina (diabetes insipidus central) como primeira manifestação de histiocitose de células de Langerhans: relato de caso
Introduction: Langerhans cell histiocytosis (LCH) is a rare clonal neoplasm of the mononuclear phagocyte system characterized by proliferation of CD1a⁺/Langerin⁺ myeloid dendritic cells and activating mutations in the MAPK/ERK pathway (such as BRAF V600E and MAP2K1). Involvement of the …
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The Effects of Chronic Stress and Exercise on Mouse Pancreatic Islet of Langerhans Morphology and Muscle Atrophy Gene Expression
Chronic stress has been implicated as a possible contributing factor to the onset of Type 2 Diabetes Mellitus through its negative effects on peripheral insulin sensitivity and the insulin producing beta cells of the pancreas. Exercise could serve as a possible countermeasure to the damaging …
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Mechanism of Insulin Release From Islets of Langerhans in a Rat Model of Normal Infants and Infants of Diabetic Mothers
Neonatal hypoglycemia is common in infants of diabetic mothers (IDM). The hypoglycemia is believed to result from persistent insulin hypersecretion due to the elevated glucose concentration in utero. The mechanism for the hypersecretion of insulin is not known. The glucose sensing mechanism in the …
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Phänotypische und funktionelle Untersuchung der Expression und Funktion des Mannoserezeptors auf Langerhans-Zellen und auf Inflammatorischen Dendritischen Epidermalen Zellen (IDEC) sowie auf Monozyten und auf in vitro generierten dendritischen Zellen
… Jahren wurde in der entzündlichen Haut neben den Langerhans-Zellen die Existenz einer weiteren Art dendritischer Zellen, der sogenannten Inflammatorischen Dendritischen Epidermalen Zellen (IDEC) herausgearbeitet. Über Herkunft, Verwandtschaft zu anderen Zellarten und Funktion der IDEC ist bislang …
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Outcomes of children with biopsy-proven Langerhans cell histiocytosis (LCH) treated at the Red Cross War Memorial Children's Hospital from 1998 – 2017
Background: Langerhans Cell Histiocytosis (LCH) is a rare histiocytic disorder characterised by the infiltration of a single organ or multiple organs by cells phenotypically similar to Langerhans cells. The number and type of systems involved affect the outcome and the longer the maintenance …
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Immunohistochemical analysis of a panel of human and murine markers on xenografted human vaginal mucosa: a comparative study
… collagen type IV, laminin, elastin, fibronectin,Langerhans cells and VEGFR-3. Murine markers included collagen type IV, laminin,fibronectin, Langerhans cells and VEGFR-2. Staining intensities were quantified and statistically analysed using one-way ANOVA with subsequent Friedman’s test for …
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