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Showing 1 to 2 of 2 for “"Lambda Exonuclease"”.
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Novel enzymatic methods of DNA detection using enhanced Raman scattering
… This primarily involved implementing the enzyme lambda exonuclease in a target cycling strategy, alongside DNA labelled with a donor and acceptor FRET pair for use in fluorescence detection. This enzyme was also utilised within a nanoparticle assembly system, whereby oligonucleotides were …
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Advancing Technologies for Precision Medicine: From Liquid Biopsy to Single-Molecule DNA Sequencing
… requirements, we investigated a thermoplastic exonuclease time-of-flight (XToF) nanopore sensor for single-molecule DNA sequencing using resistive pulse sensing (RPS). This nanopore sensor requires a highly processive exonuclease enzyme to sequentially cleave nucleotides for detection. …