Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 126 for “"Lactones"”.
-
Raman Studies of Acyl-Homoserine Lactones
… for the detection of N-acyl homoserine lactones (AHLs), which are quorum sensing molecules used in bacterial communication. The advantage of using Raman spectroscopy over other techniques is the possibility of in-situ detection of these molecules within their natural environment. The …
-
Broad-Spectrum Synthesis of Enantiomerically Pure Lactones
… approach that affords both enantiomers of chiral lactones is described. The key step involves the automated multigram chromatography of diastereomeric derivatives of a racemic intermediate. The generality of the method is demonstrated by the synthesis of ring-saturated lactones of three different …
-
Diastereomeric Interactions of Sulfoxides, Lactones and Aryl Trifluoromethyl Carbinols
Made available in DSpace on 2014-12-13T20:10:02Z (GMT). No. of bitstreams: 1 7709188.pdf: 3101030 bytes, checksum: 861440f74c5e31ae7326a4ba5123666b (MD5) Previous issue date: 1976
-
The Synthesis of Lauraceae Lactones: Obtusilactones, Litsenolides, and Mahubanolides
Phenylselenenyl esters (methyl esters of 2-phenylselenenylhexadecanoic, 2-phenylselenenyloctadecanoic, and 2-phenylselenenyl-13-tetradecadienoic acids) were used as acrylate (alpha)-anion synthons in aldol addition reactions. The last acid above, bearing the terminal double bond, was synthesized by …
-
Halo Enol Lactones as Enzyme-Activated Irreversible Inhibitors of Alpha-Chymotrypsin: I. The Effect of Lactone Substitution Pattern. Ii. Alpha - Amino-Functionalized Lactones
Halo enol lactones with a phenyl group situated (beta) or (gamma) to the lactone carbonyl group were prepared to compare their effectiveness as enzyme-activated irreversible (suicide) inhibitors for (alpha)-chymotrypsin with the activities of the corresponding (alpha)-substituted lactones. The …
-
Development of metabolic pathways for the biosynthesis of hydroxyacids and lactones
… for the production of hydroxyacids and their lactones in multiple microbial systems. These compounds see widespread use in the production of pharmaceuticals, polymers, and fine chiral intermediates. First in this thesis, strategies and tools for metabolic pathway design are discussed. This is …
-
Contribution to the elucidation of the anti-inflammatory activity of Sesquiterpene Lactones
To analyze the mechanism by which sesquiterpene lactones (SLs) inhibit DNA binding of the transcription factor NF-kB, the role of cysteine residues in its DNA binding domain was tested using single amino acid mutants of the p65 subunit. The results confirm that p65 is alkylated by SLs, and that the …
-
New Pre-Catalysts for Olefin Polymerisation and Ring-Opening Polymerisation of Lactides/Lactones
A number of pre-catalysts featuring phenoxyimine, phenolate and calixarene ligand systems have been synthesized, characterised and screened for their ability to polymerize α-olefins or ring open polymerize (ROP) cyclic esters. The treatment of a number of related phenoxyimine ligands (L1H – L3H, …
-
Synthesis of beta-lactones, II. Use of templated helices to determine Zimm-Bragg parameters
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1997.
-
Selective Synthesis of Trans-fused Lactam-Lactones by Vicinal Difunctionalization of Readily Affordable Allylic Lactams
… medicinal properties. Specifically, lactams and lactones are the respective luminaries of the antibiotic and flavor worlds. However, the synthesis of fused lactams-lactones, especially those bearing <em>trans</em>-fusion, is challenging from the standpoints of chemoselectivity, stereoselectivity, …
-
Identification and characterization of mint lactones: trace-level odor-important aroma compounds in peppermint oil
Made available in DSpace on 2016-11-10T18:27:49Z (GMT). No. of bitstreams: 2 MCKENNA-THESIS-2016.pdf: 1170791 bytes, checksum: 0bd5f4c4113603e35685b270c9aa40b5 (MD5) LICENSE.txt: 4213 bytes, checksum: 8065b1d0e69f25f20908be9acb180f53 (MD5) Previous issue date: 2016-07-13
-
Synthetic and chromatographic study of the spiro-lactams and spiro-lactones based on a 9',10'-dihydro-(9,10)-ethanoanthracene Diels-Alder adduct. Application of flash vacuum thermolysis towards synthesis of exo-methylene lactones and lactams
Synthesis of a variety of spiro-lactams and spiro-lactones which are based on a 9$\sp\prime$,10$\sp\prime$-dihydro- (9,10) -ethanoanthracene Diels-Alder adduct has been performed. Control of relative stereochemistry at the C2 and C2, C3 carbons on the lactone ring during synthesis of the …
Page 1 of 7