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Showing 1 to 20 of 28 for “"Laboratory mice"”.
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Mechanisms of Compass Orientation in C57BL/6 Laboratory Mice
… The goal of this research was to explore whether laboratory mice could use either magnetic or auditory cues for compass orientation. The results indicate that mice are able to learn to position their nest using a magnetic compass. The development of a magnetic compass assay in laboratory mice will …
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Selection for milk somatic cell count in laboratory mice
… lines (high line = HSCC, low line = LSCC) of mice. Seven secondary traits (milk yield, total white blood cell count, percentage of phagocytic cells in blood, endotoxin challenge response, percentage of females littering, number of young born alive, and percentage of young surviving to weaning) …
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Genetic architecture of reproductive and growth traits in laboratory mice
… effects for reproduction and growth traits in mice. Two selected lines of mice, extremes in phenotype for gain from 21 to 42 days of age, were used in a triple test cross design. The high line had completed 24 generations of selection for increased postweaning gain while the low line was three …
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Chromosome identification and analysis in selected lines of laboratory mice
Chromosome preparations from 102 ICR albino mice were examined using a modified trypsin Giemsa staining technique. The mice were from four lines selected for maximum rate of post-weaning gain (28 generations), one line selected for minimum rate of post-weaning gain (25 generations), and two …
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A study of somatic cell concentrations in milk of laboratory mice
… low line or LSCC) and one control line (CSCC) of mice. Distribution of milk SCC in mice was 4 to 5 times the distribution in Holsteins. The shape of the lactation curve of mice was similar to that of Holsteins with maximum yield at day 7 (2.06 gms). The phenotypic regression of lactation milk …
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Lowered reproduction efficiency as a correlated response to selection for increased post-weaning gain in laboratory mice
… the causes of lowered reproductive efficiency in mice selected for increased post-weaning gain. Four experimental groups were established: (1) Group C, the two control lines; (2) Group S, the four selected lines; (3) Group CS, the F₁ progeny from the 4 control line X selected line crosses; (4) …
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A study of the effects of sitosterol ingestion on the serum cholesterol concentrations of two genetically different strains of laboratory mice
… that occlude coronary arteries in man and laboratory animals. It is generally agreed that hypercholesterolemia favors the appearance of atherosclerotic lesions.<sup>1<1</sup></p><p>In recent years, much information has been accumulated regarding the factors which affect the serum …
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Line characterization and evaluation of genetic parameters of serum cholesterol levels, activity, feed intake, growth and body moisture in selected and unselected lines of laboratory mice
… levels (SCL) were recorded for 102 male mice, and voluntary physical activity and SCL were recorded for 113 male mice from lines selected for 22 generations for maximum 21- to 42-day gain (H), minimum 21- to 42-day gain (L), and a random-bred control (C). Heritability (h²), phenotypic and …
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Studies of Susceptibility of Broad-Headed Skinks (<em>Eumeces laticeps</em>) and Laboratory Mice (<em>Mus musculus</em>) to Strain MI-2 of <em>Borrelia burgdorferi</em> and Vector Competence of the Tick <em>Ixodes scapularis</em>
… contrast, seven of eight (88%) needle-inoculated mice were successfully infected with MI-2 strain spirochetes. Furthermore, nymphs that resulted from larval feedings on culture positive mice successfully transmitted <em>B. burgdorferi</em> to 76% of the mice that they were allowed to feed on.</p> …
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The Mouse Magnetic Compass
… and the magnetite based mechanism (MBM). C57BL/6 laboratory mice can rely on directional information from the magnetic field to position their nests and to solve a water maze task. The primary objective of this research was to characterize the magnetic compass of C57BL/6 laboratory mice in the …
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Vector Potential of Two Southeastern Tick Species (Acari: Ixodidae) for a Northeastern Strain of the Lyme Disease Spirochete, <em>Borrelia burgdorferi</em> Sensu Stricto
… & Brenner (B.b.s.s.) were compared under laboratory conditions. Also, the infectivities via needle injection, of several southeastern <em>Borrelia</em> <em>burgdorferi</em> sensu lato (B.b.sA.) isolates in rodents were examined. Ixodes minor larvae were fed on isolate SH2- 82 (B.b.s.s) …
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Design of a constraint device for compliant bodies using quasi-conformal contact surfaces as applied to mouse imaging
… bodies, specifically for the holding of mice in optical imaging setups. The direct application of this work is the restraint of laboratory mice for biological imaging of micron- and submicron-scale biological structures. No existing research has measured the shear stiffness of mouse …
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The role of NK cells in selectin-dependent tumor suppression
… are critical for immune cell trafficking. In our laboratory, mice lacking all combinations of selectins have been generated. Previous work from our laboratory has demonstrated that, in the absence of selectins, human tumors transplanted subcutaneously into Rag2'- mice grow significantly larger. …
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Quantitative genetics and metabolomics of aerobic metabolism
… and BMR in a genetically heterogeneous stock of laboratory mice. Narrow-sense heritability (h2) was approximately 0.38+0.08 for body mass, 0.24+0.07 for whole-animal MMR, 0.26+0.08 for whole-animal BMR, 0.16+0.06 for mass-independent MMR, and 0.19+0.07 for mass-independent BMR. All h2 estimates …
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The Effects of Microwave Radiation on the Infectivity of Trichinella Spiralis
… of "Trichinella spiralis" in young, white, laboratory mice were studied. Procedure. Mice were divided into two groups: 1) mice receiving isolated, irradiated larvae and 2) mice receiving larvae which were isolated from irradiated carcasses. These two groups were further subdivided by the …
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The Immune Response of the Laboratory Mouse Subjected to 'Trichinella Spiralis' and Prednisone
… prednisone on the immune system of young white laboratory mice infected with Trichinella spiralis. Procedure. Mice were divided into the following four groups: 1) T. spiralis-infected, 2) prednisone-injected, 3) T. spiralis-infected and prednisone-injected, and 4) normal controls. Three days …
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Use of Inbred Strains for the Study of Individual Differences in Pain Related Phenotypes in the Mouse
… phenotypic information about inbred strains of laboratory mice is being collected and assembled in large databases. Sophisticated mining of this information can be useful in generation of hypotheses regarding the sources and nature of phenotypic variability, both environmental and genetic. As …
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Delineating the Role of CD244 in NK Cell Cytotoxicity and the Contribution of Ly108 to Thymocyte Development
… antibodies. Analysis of common strains of laboratory mice revealed the existence of two stable haplotypes (b and z) of the SLAM family gene cluster. Given recent studies identifying polymorphisms in the SLAM family in humans, we have determined how polymorphisms in the SLAM family can …
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The genetics of atrial septal defect and patent foramen ovale
… for this disorder. Previous studies of inbred laboratory mice showed an association between patent foramen ovale (PFO) and measures of atrial septal morphology, particularly septum primum length (“flap valve length” or FVL). In humans, PFO is associated with cryptogenic stroke and migraine, and …
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