Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 156 for “"Laboratory Sciences"”.
-
Quantitative analysis of K-ras mutation in urine as an indicator of disease status in patients with stage II or higher colorectal cancer
… State University. Department of Clinical Laboratory Sciences, 2008
-
A Model for International Clinical/Biomedical Science Programs
… and mutual credentialing systems for laboratory professionals. It also examined a potential transatlantic student exchange program for laboratory sciences students. The study addressed key problems confronting the laboratory profession, such as workforce shortages, mobility issues, and …
-
Heart rate variability (HRV) as a predictor of anemia in premature infants using Artemis
… infants, and current detection practices rely on laboratory testing of blood samples. This thesis introduces a Clinical Decision Support System (CDSS) framework that utilizes high frequency streaming physiological data and laboratory information for clinical insights through visual analytics. The …
-
Development and initial testing of a virtual simulation training module to teach microtomy
Background: Microtomy is a procedure that medical laboratory technologists (MLTs) use to cut tissue samples. The aim of this thesis is to use the think-aloud protocol to develop a virtual simulation training module for students to learn microtomy. Methods: A think-aloud protocol was conducted with …
-
Implementation of a Clinical Laboratory Science Internship Program at Dominican University of California
<p>The demand for California licensed clinical laboratory scientists (CLS) is rapidly growing due to increased CLS retirement, a high CLS vacancy rate, and decreased California approved training programs. With only 13 approved training programs in California, hundreds of qualified applicants are …
-
A Comparative Study of the Pathology and Pathophysiology of Severe Malaria in a Non-Human Primate Model
… the Armed Forces Research Institute of Medical Sciences in Bangkok, Thailand, compounded with data and material from a series of prospective experimental studies, the work in this thesis sought to fully characterize and describe the pathology and pathobiology of the P. coatneyi/Rhesus macaque …
-
Developing/testing a new approach for assessing rapid visual identification of hematological cells using principles of visual cognition: a health science education study
… skills used in the field of Clinical Laboratory Sciences (CLS). A dual format exam was administered to both novices (students) and experts (laboratory professionals). Format 1 was similar to current assessment formats, simply presenting a series of single WBC images for identification. …
-
Demographic Characteristics and Academic Measures as Predictors of Success on the American Society for Clinical Pathology (ASCP) Medical Technologist Certification Examination
… of the Andrews University Program for Clinical Laboratory Sciences. The 233 subjects were from 53 different birth countries. The relationships between Certification Examination scores and both demographic characteristics and academic measures were analyzed by chi square, analysis o f variance, …
-
Heterologous production of recombinant peptidylglycine α-amidating monooxygenase for the production of biosimilar α-amidated peptides
A biological method for peptide synthesis provides increased production capacity of inexpensive peptide pharmaceuticals with environmentally safe procedures relative to current chemical peptide synthesis. Most precursor peptides are readily produced from yeast and bacterial systems using …
-
Exploring the phylodynamics, genetic reassortment and RNA secondary structure formation patterns of orthomyxoviruses by comparative sequence analysis
RNA viruses are among the most virulent microorganisms that threaten the health of humans and livestock. Among the most socio-economically important of the known RNA viruses are those found in the family Orthomyxovirus. In this era of rapid low-cost genome sequencing and advancements in …
-
A citywide, clonal outbreak of Pseudomonas aeruginosa during a drought
Background Outbreaks of community-acquired Pseudomonas aeruginosa are typically small and localized. We investigated an increase in P. aeruginosa clinical isolates in Cape Town, South Africa during a severe drought. Methods Cases were defined as P. aeruginosa isolated from any clinical sample, and …
-
Evaluation of two SARS-CoV-2 immunoassays
… in the Groote Schuur Hospital virology/chemistry laboratory, as well as other National Health Laboratory Service (NHLS) laboratories in South Africa. Methods: We performed a verification study using de-identified remnant serum or plasma samples. Standard verification experiments including …
-
Retrospective review of gunshot injuries at Salt River mortuary, Cape Town, Western Cape
The use of firearms to inflict fatal trauma is a social, economic, and public health concern globally. In South Africa, firearm-related injuries (FRIs) have become the leading cause of unnatural death. Despite this, few studies have investigated the demographic, geographic and temporal distribution …
-
Opinions and practices of medical specialists concerning medical genetic services at the Pietersburg and Mankweng academic teaching hospitals in the Limpopo Province
… the province and the provincial National Health Laboratory Service does not have a genetics diagnostic laboratory. Thus, there are currently no medical genetic services available or outreach programmes within either the public or private healthcare systems in Limpopo. Any patients requiring …
-
Diagnostic yield of tuberculosis investigations on bone marrow biopsy samples in HIV positive patients at Groote Schuur Hospital
Background: Acid fast bacilli (AFB) staining on bone marrow samples has low sensitivity for diagnosing HIVassociated tuberculosis and Tuberculosis (TB) culture results may be delayed. The GeneXpert® MTB/RIF Ultra assay may provide a more sensitive diagnostic test on bone marrow biopsy samples. …
-
The characterization of Lowe Syndrome in a South African cohort
Oculocerebrorenal or Lowe Syndrome (OMIM #309000) is an X-linked recessive condition characterized by a triad of congenital cataracts, proximal renal tubular dysfunction, and variable central nervous system involvement. Nearly all affected boys will be hemizygous for a pathogenic variant in the …
-
Characterizing the cellular latent reservoir of HIV-1 and the effect of immune activation on characteristics of the reservoir
Since the advent of antiretroviral therapy (ART) and the resultant suppression of viraemia in the majority of people living with HIV-1 (PLWH) on ART, HIV-1 infection has become manageable and PLWH have similar life expectancies as uninfected persons. However, ART is not curative, is needed …
-
The role of pulmonary innate and adaptive immune responses to helminth infection
Immunity to nematode infections requires a host T helper 2 (Th2) response promoted by epithelial cell driven IL-33 induction of cytokine secretion of Interleukin (IL)-4, 5 and 13 by a range of immune cells including innate lymphoid cells type 2 (ILC2s) and CD4+ T cells. This induces effector …
-
The role of Lymphoblastic leukemia 1 (Lyl1) in Mycobacterium tuberculosis (Mtb) infection
Lymphoblastic leukemia 1 (Lyl1) is a well-studied transcription factor known to exhibit oncogenic potential during various forms of leukemia. Since its discovery in 1989, many reports have been published describing its relationship with cancer as well as demonstrating its function during …
-
Human myeloid cell and innate lymphocyte responses to mycobacterial vaccination or infection
We investigated immune responses beyond conventional T cells in the context of BCG vaccination and tuberculosis disease.
Page 1 of 8