Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Label-free quantitation"”.
-
Proteomic Map of ER+ Breast Cancer Cell Cycle
… mass spectrometry (LC-MS/MS) followed by a label-free quantitation approach, i.e., spectral counting, for differential protein expression analysis. The study was divided into three distinct parts: 1) qualitative profiling of MCF-7 cells arrested in the G1-phase and released into the S-phase …
-
Protein Set for Normalization of Quantitative Mass Spectrometry Data
… for peptide and protein identification and quantitation. With the advent of soft ionization methods, such as electrospray ionization and matrix assisted laser desorption/ionization, mass spectrometry has opened a new era for protein and proteome analysis. Due to its high-throughput and …
-
Generating a proteomic profile of neurogenesis, through the use of human foetal neural stem cells
… NES and NS cells were compared using SILAC labelling. In addition, each cell line was differentiated for 12 days, 6 timepoints were taken and compared using label free quantitation. Results 4677 proteins were quantitated with 473 differentially expressed, revealing fundamental differences …
-
QUANTITATIVE PROTEOMIC APPROACHES TO STUDY DRUG MECHANISM OF ACTION
… development with an alkyne moiety that could be labelled with a fluorescent-azide for target engagement detection and quantitation in native environments and a desthiobiotin-azide molecule for identification of the inhibitor off-target binders and proteome-wide selectivity. The functionalization …
-
Neuropeptidomics: MS-base peptide identification and quantitation study
… applied for peptide identification and quantitation. Neuropeptide production regulated by DIMM-dependent genetic mechanism and post-translational processing through alpha-amidation has been studied with different MS-based approaches such as matrix-assisted laser desorption/ionization …