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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 126 for “"Lab on a Chip"”.
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Electrodynamic droplet actuation for lab on a chip system
… work presents the development of electrowetting on dielectric and liquid dielectrophoresis as a platform for chemistry, biochemistry and biophysics. These techniques, typically performed on a single planar surface offer flexibility for interfacing with liquid handling instruments and performing …
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A deep sea lab on a chip chemical sensor
The measurement of chemical concentrations within the oceans is crucial for our understanding of its biogeochemical processes. Such data is vital for; studies of climate and environment change; natural resource management; assessment of pollution, human impact and biodiversity. Current measurement …
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CMoS lab-on-a-chip devices for individual cell biology
The development of microlectronic lab-on-a-chip devices (LOACs) can now be pursued thanks to the continous advances in silicon technology. LOACs are miniaturized devices whose aim is to perform in a more efficient way specific chemical or biological analysis protocols which are usually carried out …
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Eis analysis of shear enhanced microfluidic lab-on-a-chip device
… sensors and biosensors have received much attention owing to the feasibility demonstrated regarding instrumental simplicity, decent cost, and portability during the detection of a wide range of biological and pharmaceutical macromolecules. Carbon-based nanomaterials, including carbon nanotubes, …
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Monitoring single heart cell biology using lab-on-a- chip technologies
Abstract There has been considerable interest in developing microsensors integrated within lab-on-a-chip structures for the analysis of single cells; however, substantially less work has focused on developing "active" assays, where the cell‘s metabolic and physiological function is itself …
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Multifunktionsfeldeffekttransistoren zur Strömungs-, Chemo- und Biosensorik in Lab on a Chip-Systemen
… ein neuartiges FET -Sensorelement zum Nachweis von Flüssigkeitsbewegungen vorgestellt, das zudem bei Bedarf auch als Chemo- oder Biosensor fungieren kann. Das Einsatzspektrum von FET-basierten Sensoren in Lab on a Chip-Systemen wird dadurch entscheidend erweitert. Bei dem entwickelten FET-Sensor …
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Engineering surfaces to control microfluidic flow in lab-on-a-chip devices
Laboratory-on-a-chip technologies have received growing interests in last 20 years as a method to miniaturise, parallelise, and optimise chemical reactions and biological detections normally carried out at the macro-scale. As a generic tool, microfluidics can be presented as the science of …
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Manufacturability of lab on a chip devices: tolerance analysis and requirements establishment
Decisions made during the first stages of the design process can have an impact on the cost, quality and performance of a product. Variation in assemblies, if not managed correctly during the design stage, can have a negative impact on the success of the product. This work analyzes the Daktari CD4+ …
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Integrated microfluidics, heaters, and electronic sensors for Lab-on-a-Chip applications
… microfabricated suspended heaters and electronic field effect sensors have been successfully integrated on a single device chip. This integration enables spatial cycling of as little as 11nL of reagents over different thermally isolated temperature zones, to be coupled with the field effect …
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Electrokinetically Driven Mixing in a Microchamber for Lab-on-a-Chip Applications
… Driven Mixing in a Microchamber for Lab-on-a-Chip Applications Narayan Sundaram Abstract Micro-Total-Analysis-Systems (μTAS) have been the focus of recent world wide research due to their varied applications. Much of the motivation for the development of μTAS stems from applications …
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Ultrasensitive CMOS-compatible lab-on-a-chip integrated photonic sensors with wideband operation
… rapid development of the field of integrated photonics enables the opportunity of realizing integrated and compact sensing systems with fast analysis, low cost, and potential for mass production. The focus of this dissertation is to develop key building blocks for the lab-on-a-chip (LOC) sensing …
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Real time, integrated, paper based temperature sensor for lab on a chip device
Temperature measurement and manipulation is a critical factor in a wide range of applications like Point Of Care Diagnostics (POC's), Polymerase Chain Reaction (PCR), Temperature Gradient Focusing (TGF) to cite few prominent examples. In the past decade, researchers have used various techniques to …
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Portable Microfluidic Platform Employing Young-Laplace Pumping For Multiplexed Lab-On-A-Chip Applications
… relevant in the current field of medicine. “Lab-on-a-chip” devices are of special interest, as they enable the user to quickly perform tests with small concentrations of sample/analyte. The invention of affordable solutions to accurately perform sample preparation and analysis without the …
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A Lab-on-a-chip System for the Standardised Characterisation of Membrane Active Antimicrobials
The continuing evolution of bacterial resistance against commercially available antibiotics is recognised as a global health threat, and the discovery of novel antimicrobials is urgently required. Antimicrobial peptides (AMPs) are emerging as important players in the fight against antibiotic …
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Manufacturing of lab-on-a-chip devices : characterizing seals for on-board reagent delivery
… Reagents held in an aluminum pack are released on the opening of a fluidic seal. Fluidic seals, controlling the flow of reagents, are characterized to reduce anomalies in the desired flow pattern. The nature of the current seal was investigated. Four seal patterns - line hemisphere, line flat, …
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Development of a Digital Microfluidic Lab-on-a-chip for Analysis of Atmospheric Inorganic Ions
A microfluidic device consisting of a Lab-on-Chip (LoC) was designed for on-line analysis of sulfate, ammonium and nitrate in atmospheric air samples. The LoC has the ability to integrate and automate collection (via impaction), extraction and analytical detection of these three major inorganic …
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Development of an automated and scalable lab-on-a-chip platform with on-chip characterization
… a fluid-handling technique that enables precise control of drops on an array of electrodes using electrostatic forces. In contrast to most other lab-on-a-chip technologies (e.g., channel-based microfluidics), DMF is highly reconfigurable (i.e., function is defined by software and not by the …
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Application of microfluidic emulsion technology to biochemistry, drug delivery and Lab-on-a-Chip programmability
This research applies microfluidic emulsion technology to three diverse problems; biochemistry, drug delivery and lab-on-a-chip programmability. These subjects represent distinct research programs, but the underlying physics of droplet formation, transport and control at low values of the Reynolds …
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Manufacturing of Lab-On-a-Chip devices : variation analysis of liquid delivery using blister packs
Components for on-chip storage and delivery of liquid reagent are necessary for many commercial applications of lab-on-a-chip technology. One such system uses a 'blister pack' that is pushed by an actuator. Over the course of product development, Daktari Diagnostics had completed nominal design of …
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