Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"La Crosse virus"”.
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Overwintering Mechanisms of La Crosse Virus Vectors
The La Crosse virus (LACV) is an emerging pathogen in the Appalachian region of the United States. The virus maintains a complex natural cycle through horizontal transmission with sciurid rodents and Aedes mosquitoes in Virginia. Transovarial transmission also occurs in this host-parasite system …
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Molecular analysis of La Crosse virus transcription and replication in host cells
La Crosse (LAC) virus is an arthropod-borne virus (family Bunyaviridae, genus Orthobunyavirus) transmitted by Aedes triseriatus mosquitoes and is an important cause of pediatric arboviral encephalitis in the United States. Like other arthropod-borne viruses, LAC virus can be very cytolytic in …
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Dynamics of La Crosse virus: Surveillance, Control and Effect on Vector Behavior
La Crosse virus (LACV) encephalitis is the most common and important endemic mosquito-borne disease of children in the U.S. with an estimated 300,000 annual infections. The disease is maintained in a zoonotic cycle involving the eastern treehole mosquito, Aedes triseriatus and small woodland …
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Forest disturbance, mosquito vector ecology and La Crosse virus dynamics in southwestern Virginia
… influence of forest canopy disturbance (FCD) on La Crosse virus (LACV), leading cause of US pediatric arboviral encephalitis, is critical to understand in landscapes where forests are periodically harvested. Southwestern Virginia is part of an emerging focus of this interior forest bunyavirus. I …
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Transmission of La Crosse Virus in Southwest Virginia: Role of Accessory Vectors, Microfilarial Coinfection and Canine Seroprevalence
… become an emerging focus of activity for La Crosse (LAC) virus, a mosquito-transmitted arbovirus in the California serogroup of Bunyaviruses. In 2005 and 2006, ovitrap surveys were conducted to access the spatiotemporal oviposition activity of LAC virus vectors Aedes triseriatus, Ae. …
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Comparative Transmission and Pathogenesis of La Crosse Virus (LACV) Lineages and Evidence for LACV Circulation in Virginia Wildlife
La Crosse virus (LACV) is a mosquito-borne arbovirus that is the main cause of pediatric encephalitis in the United States in children under 16. LACV is maintained in hardwood forests utilizing Aedes spp. mosquitoes, primarily Aedes triseriatus, and Sciuridae vertebrate host species, primarily the …
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La Crosse Virus in Southwestern Virginia: Role of Exotic Mosquito Species and Effect of Virus Infection on Feeding
The family Bunyaviridae is the largest of vertebrate diseases and includes the mosquito-borne disease La Crosse (LAC) virus. Vectors include the major vector Aedes triseriatus and two accessory vectors Aedes albopictus and Aedes japonicus. In the past several decades there has been an increase in …
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Aedes Albopictus in Peoria, an Invasion by an Exotic Mosquito Vector Into an Urban La Crosse Virus Endemic Area in Illinois
… that Ae. albopictus is serving as a vector for La Crosse virus encephalitis, LAC virus continues to circulate in the sciurid amplifier host population and Ae. albopictus was shown to utilize sciurid bloodmeals. Continued surveillance is recommended to monitor the Ae. albopictus population in …
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Bionomics of Ochlerotatus triseriatus Say (Diptera: Culicidae) and Aedes albopictus Skuse (Diptera: Culicidae) in emerging La Crosse virus foci in Virginia
Recently, the number of human cases of La Crosse encephalitis (LACE), an illness caused by mosquito-borne La Crosse (LAC) virus, has increased in southwestern Virginia, resulting in a need for better understanding of the virus cycle and the biology of its vectors in the region. This project …
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La Crosse virus and Dirofilaria immitis: Abundance of Potential Vectors in Southwestern Virginia and the Effects of Dual Infection on Aedes albopictus and Ochlerotatus triseriatus
Microfilarial enhancement of viral transmission is well documented, however only one previously studied model used components that occur together in nature and therefore has realistic implications. La Crosse (LAC) virus encephalitis is the most common mosquito-borne illness affecting children in …
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Transcriptional regulation of mosquito oogenesis
… triseriatus</i> (Say), is the primary vector of La Crosse virus (LACV) in the United States. LACV is maintained in natural populations in part by transovarial transmission from infected females to their progeny. Our understanding of the innate immune response in mosquito ovaries is a fundamental …
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Morphological differentiation of eggs and comparative efficacy of oviposition and gravid traps for Aedes vectors at different habitats
Mosquito surveillance is an integral part of understanding mosquito-borne disease, including and not limited to the La Crosse virus. The primary container-inhabiting Aedeni vectors include Aedes triseritatus, Aedes albopictus, and Aedes japonicus. To better understand the efficacy of gravid traps …
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Comparative Analysis of Antiviral Responses in Mouse Embryonic Stem Cells and in Mesenchymal Stem Cells
… for cell therapy, ESC-derived cells could be placed in a wounded area that is likely to be exposed to various pathogens. However, it is not well-understood whether ESCs and ESC-derived cells have active antiviral responses against infectious agents from the environment. To answer this important …
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TISSUE ARCHITECTURE AND INTERCELLULAR COMMUNICATION: MEDIATORS OF PROTECTIVE OR PATHOGENIC INTERFERON RESPONSES
… has defined how anatomical structures and regulation of immune responses by resident immune cells contribute to this balance. However, the contribution of tissue-resident non-immune cells within these barriers remains understudied. By employing cutting edge human and mouse models, I was able to …
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INNATE IMMUNITY IN ENCEPHALITIC BUNYAVIRUS INFECTION: OVERCOMING NEURONAL VULNERABILITY
Several arthropod-borne bunyaviruses cause encephalitic disease in humans, primarily infecting neurons in the brain. Two of the most prominent examples are Rift valley fever virus (RVFV), and La Crosse virus (LACV). These viruses may preferentially infect neurons due to dampened neuronal innate …
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Human Neural Stem Cell-Derived Neuron/Astrocyte Co-Cultures as a Model System to Study Emerging Encephalitic Viruses
… fatality rates and high rates of neurologic sequelae such as behavioral changes, cognitive deficits, seizures, paralysis, or persistent infection. Relatively little is known about viral infections of cells within the central nervous system such as neurons and astrocytes. One challenge in studying …
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Evaluation of the role of plant-derived chemicals in mosquito ecology and control
… pathogens, has been extensively studied, plant-feeding is an essential element in the life histories of most mosquito species. For these species, adults of both sexes seek out and depend on floral nectar. Moreover, the larvae of the majority of mosquito species consume dead decaying plant …
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Discrete and continuous mathematical investigation of juvenile mosquito dynamics
… transmit infections such as dengue, Zika, Mayaro virus, and La Crosse virus. Curtailing these diseases is a good reason to consider control of mosquito populations. However, mosquitoes are quite hardy and spraying of pesticides is typically a short-term solution. Thus, more long-term solutions …
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Factors influencing arbovirus transmission: vector competence and the effects of virus infection on repellent response, oxidative stress, and glutathione-S-transferase activity
Zika (ZIKV), La Crosse (LACV), and Cache Valley (CVV) viruses are mosquito-vectored diseases that cause significant morbidity and mortality in humans and animals. Transmission of these viruses are dependent on numerous factors including vector competence and the effects of mosquito-virus …