Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"LXRa"”.
-
Genetic association study of interleukin 6 receptor and liver X receptor in systemic lupus erythematosus
… acute-phase reaction. Liver X receptor alpha (LXRA, NR1H3) and beta (LXRB, NR1H2) are established sensors of lipid and cholesterol homeostasis. The recent studies have reported that LXRs are involved in regulation of inflammation and immune responses. Objective: We attempted to identify single …
-
An interdisciplinary approach leveraging human genetic variation to identify novel mechanisms of liver disease and pregnancy sickness
A major aim of human genetics in both academic in industrial spheres is to translate a genetic association to a mechanistic understanding of the disease process or trait being studied. The rewards in achieving this are large – a detailed mechanistic understanding of how genetic variation affects a …