Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"LXR-alpha"”.
-
An interdisciplinary approach leveraging human genetic variation to identify novel mechanisms of liver disease and pregnancy sickness
… variants in the cholesterol sensing receptor LXRand undertook a functionally enriched human genetic association study. Using this approach, I demonstrated that loss of function mutations in LXR(Liver-X-Receptor-alpha) are a cause of hepatotoxicity in humans despite evidence of suppression …