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Showing 1 to 1 of 1 for “"LXRβ activation"”.
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Identification of a MicroRNA Network that Regulates Melanoma Metastasis and Angiogenesis by Targeting ApoE
… identified the nuclear hormone liver-X receptor (LXRβ), a known transcriptional trans-activator of ApoE, as an ideal target given its ubiquitous expression across all normal tissues as well as melanoma subtypes. Oral delivery of LXR agonists strongly suppressed melanoma tumor progression and …