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Showing 1 to 3 of 3 for “"LUHMES"”.

  1. The Effects Of Oxidative Stress On P75ntr Signaling In Dopaminergic Neurons

    … the Lund Human Mesencephalic cell line (LUHMES) was used in our study. LUHMES cells can be differentiated into mature dopaminergic neurons following a two-step differentiation procedure. The p75NTR was found to be activated and cleaved in response to 6-hydroxydopamine (6-OHDA), a …

    eku Repository record for The Effects Of Oxidative Stress On P75ntr Signaling In Dopaminergic Neurons (opens in a new tab)

  2. Neuroprotective effects of incretin mimetics upon chronic endoplasmic reticulum (ER) stress : implications for novel therapeutic pathways and opportunities in Alzheimer's disease

    … in human post-mitotic neurones from the LUHMES cell line. I have further addressed the neuroprotective and restorative effects of a novel dual incretin against the chronic and calcium-dependent ER stress. Novel dual incretin analogues have recently been developed and have displayed …

    lancaster Repository record for Neuroprotective effects of incretin mimetics upon chronic endoplasmic reticulum (ER) stress : implications for novel therapeutic pathways and opportunities in Alzheimer's disease (opens in a new tab)

  3. Towards cell replacement therapy in Parkinson’s disease. Proteoglycans and Nogo-A as modulators of axonal growth in midbrain dopaminergic neurons

    Parkinson’s disease (PD) is currently the second most common neurodegenerative disorder (after Alzheimer’s disease). PD is diagnosed on its motor symptoms, which include akinesia, bradykinesia, rigidity, postural imbalance and resting tremor. It is well established that the motor symptoms develop …

    lund Repository record for Towards cell replacement therapy in Parkinson’s disease. Proteoglycans and Nogo-A as modulators of axonal growth in midbrain dopaminergic neurons (opens in a new tab)