Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"LSCs"”.
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Regulation of Myeloid Leukemia Cells by Platelet Factor 4
Leukemic stem cells (LSCs) are thought to be the main drivers of relapse in Acute Myeloid Leukemia. LSCs ability to retain key properties of healthy hematopoietic stem cells (HSCs) means they are quiescent, chemo-resistant, and able to repopulate eradicated leukemic blasts, making LSCs an important …
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Using Live Sequence Chart Specifications for Formal Verification
… investigating the use of Live Sequence Charts (LSCs), a graphical and intuitive language directly suited for expressing communication behaviors of a system as the specification language for a system under test. The research presents two methods for using LSCs as a specification language: first, …
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Engineering the optical properties of luminescent solar concentrators at the molecular scale
Luminescent Solar Concentrators (LSCs) concentrate solar radiation onto photovoltaic (PV) cells using an inexpensive collector plate to absorb incoming photons and waveguide fluorescently re-emitted photons to PVs at the edge. This thesis addresses the two main energy loss mechanisms in LSCs, …
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Lifetime and efficiency improvement of organic luminescent solar concentrators for photovoltaic applications
… concentrators, luminescent solar concentrators (LSCs) have significant industry application potential. Materials used in LSCs are inexpensive, the solar cell size is reduced and no tracking of the sun is required. In an LSC, the incident sunlight is absorbed by luminescent species, such as …
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Eliminating Acute Myeloid Leukemia Stem Cells by Targeting the Niche Microenviromnent: Co-Inhibition of TNF/IL1- JNK and NF-κb
<p>Leukemia Stem Cells (LSCs) from Acute Myeloid Leukemia (AML) require the activity of the transcription factor NF-kB to maintain stemness and drive tumor formation. Blocking NF-kB can preferentially eliminate LSCs in vitro with minimal effects on healthy Hematopoietic Stem and Progenitor Cells …
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GENERATION OF SYNTHETIC ANTIBODIES AS POTENTIAL THERAPEUTICS TO BLOCK IL3–MEDIATED INNATE IMATINIB RESISTANCE IN CHRONIC MEYLOID LEUKEMIA
… of TKIs in eradication of leukemic stem cells (LSCs). Accumulating evidence demonstrates that bone marrow stromal cell secreting factors, such as Interleukin 3 (IL3) hinder TKI activity and support CML–LSCs to survive the therapy with innate drug resistance. Therefore, the overall objective of …
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Putative Roles of Cd200 In The Leukemogenesis and Immune Evasion of Leukemia Stem Cells
… transplant serves as proof-of-principle that AML LSCs can be eliminated by the immune system, the translation of existing immunotherapies to AML have been met with limited success. Consequently, understanding and exploiting the unique immune mechanisms of AML LSCs is critical. To identify novel …
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Primary culture of human limbal-corneal epithelial cells under different conditions
… epithelium is renewed by limbal stem cells (LSCs). Absence, damage or loss of the LSC population leads to the painful and blinding condition of LSC deficiency (LSCD). In vitro expansion of LSCs is an increasingly well recognized treatment modality for LSCD. The purpose of this study was to …
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Optimization of luminescent solar concentrators
… improvement. Luminescent Solar Concentrators (LSCs) are part of this effort. They are used to improve the incident light influx into the solar cell with the help of a polymer matrix with luminescent dye molecules. These systems offer an opportunity for increased power generation without the use …
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Forster Resonance Energy Transfer in materials used in Luminescent Solar Concentrators
Luminescent solar concentrators (LSCs) or fluorescent concentrators are a cheap and efficient way to concentrate sun light into a photovoltaic cell. Solar cells can be made to perform better under high illumination conditions and LSCs can be employed to perform this task. Effective utilization of …
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Applications of spectral management in optoelectronic devices
… (PVs), luminescent solar concentrators (LSCs) and light-emitting diodes (LEDs). Multiple excitation generation (MEG) – a process in which multiple charge-carrier pairs are generated from a single optical excitation - is a promising way to improve the photocurrent in photovoltaic devices …
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Design of high-performance luminescent solar concentrators based on aggregation-induced emitters in organic-inorganic hybrid waveguides
… conditions. Luminescent solar concentrators (LSCs) provide a realistic solution to such limitations. LSCs are solar-harvesting devices fabricated using a transparent waveguide that is either doped or coated with luminescent species (lumophores). They can collect large areas of solar radiation …
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Luminescent solar concentrator structures for solar energy harvesting and radiation control
… developed and characterised, namely: 1. LSCs incorporating inorganic luminophore materials into the lamination interlayer. These luminophores, when used in conjunction with spectrally-selective low-e thin-film coatings and CuInSe2 solar cells, enable most of the visible solar radiation to …
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Luminescent Harnessing of 2D Transition Metal Dichalcogenide Excitons
… harvesting with luminescent solar concentrators (LSCs). Newly prepared monolayers are however susceptible to chalcogen atom vacancies, which quench bright excitons and trap mobile charges, amounting to material with poor PL yields and low mobilities, which is of little practical use. …
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Sensitized energy transfer for organic solar cells, optical solar concentrators, and solar pumped lasers
… solar cells and luminescent solar concentrators (LSCs) for the end goal of achieving a lower cost solar energy generation. This thesis explores three new device architectures to overcome limited solar absorption in singlet-exciton-fission based solar cells and neodymium based LSCs. The process of …
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Perovskite interfaces with protective zinc compounds – DFT computation and related experiments
… efficient luminescent solar concentrators (LSCs), paving the way for scalable solar energy harvesting in urban environments.
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Role of Polycomb Group Protein Mel18 in Hematopoietic Stem Cell Maintenance
… stem cells (HSCs) and leukemia stem cells (LSCs) self-renewal, the role of Mel18 in normal and malignant hematopoiesis is not fully understood. Based upon our previous studies and the literature, I hypothesized that Mel18 inhibits HSC self-renewal and proliferation but promotes HSC …
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High efficiency luminescent solar concentrator with interconnected gallium indium phosphide micro solar cells
… was proposed. Managing photon losses in LSCs is a considerable challenge as is evident from our outdoor test. The highest concentration factor achieved so far is several orders of magnitude lower than the thermodynamic limit, despite extensive research on improving individual components …
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Quantum dot polymer composite materials for light management in optoelectronic devices
… spectrum. We have examined the performance of LSCs utilizing CdSe/CdS core-shell QDs, with significantly reduced absorption-emission overlap and long propagation distances in the waveguide. Furthermore, a distributed Bragg reflector dramatically mitigates the negative impact of scattering in …
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High quality optical and optoelectronic materials for efficient light management and solar spectrum control and conversion
… a liquid crystal display (LCD). Strategies from LSCs are exploited to design the emissive component, quantum dots embedded in a polymer waveguide. The quantum dots used here have high quantum yields and narrow bandwidths, which are necessary if an RGB display is to be realized. Additionally, the …
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