Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"LRP"”.
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The in planta role of the global regulator Lrp in the bacterial phytopathogen Pantoea stewartii subsp. stewartii
… RNA-Seq study resulted in the selection of lrp as a gene of interest for further analyses. A reverse genetics approach was used for the creation of a strain containing the in-frame deletion of lrp, as well as a revertant strain. The strain with the deletion of the lrp gene showed reduced …
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In vivo study of the expression of the genes serA and gltD regulated by Lrp (Leucine-responsive regulatory protein) in Escherichia coli K-12
The plasmid pBAD22 lrp $\rm Cm\sp{R}$ carrying the lrp coding region immediately downstream from the $\rm p\sb{BAD}$ promoter was used to vary intracellular concentrations of Lrp. The expression of the genes serA and gltD was determined in the presence of different concentrations of Lrp. The …
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Role of Hepatic Lipoprotein Receptor-related Protein 1 (LRP-1) on Amyloid Beta Pathology in a Mouse Model of Amyloidosis
… lipoprotein receptor related protein-1 (LRP1) which is the major receptor involved in the peripheral clearance of Aβ. Our preliminary work on the same lines showed a reduction in hepatic LRP1 in alcohol-fed mice with a concomitant increase in brain Aβ. Therefore, we hypothesized that a …
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Investigating the role of Leucine-Responsive Regulatory Protein (Lrp) in the production and regulation of specific virulence factors in Pseudomonas aeruginosa
… virulence and nutrient acquisition. Previously, Lrp has been shown to bind to PQS in <em>P. aeruginosa</em>, a key player in quorum sensing, and when <em>lrp</em> is knocked out, there is a reduction in these quorum sensing virulence factors. Leucine-responsive regulatory protein (Lrp) is a known …
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Klonierung, Expression und funktionelle Charakterisierung eines Minirezeptors aus der Domäne II des LDL Receptor Related Protein
Das LDL Receptor Related Protein (LRP) ist ein 600 kD großer multifunktioneller Rezeptor, der in der Leber stark exprimiert wird und Liganden aus dem Lipidstoffwechsel bindet. Zu Beginn dieser Arbeit war die Lage der Bindungsstellen von Liganden des Lipidstoffwechsels im LRP nur unzureichend …
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Cattle price risk management strategies-using computer simulation to educate Iowa producers of available tools
… options, Livestock Risk Protection Insurance (LRP), as well as Livestock Gross Insurance (LGM) for feedlot cattle. Learning about such price risk management tools can be a daunting task. Kansas State University Extension created a computer based simulation workshop to assist them in teaching …
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Characterization of the 37-kDa/67-kDa laminin receptor as the cell surface receptor for the cellular prion protein
… the human 37 kDa laminin receptor precursor (LRP), which represents the precursor of the human 67 kDa high-affinity laminin receptor (LR), was identified as a binding partner for the cellular prion protein in a yeast two-hybrid screen. In order to characterize the possible role of LRP/LR as a …
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Regulation of transcription of SerA in Escherichia coli K-12
… by leucine responsive regulatory protein (Lrp) by different mechanisms. However, very little is known about how the two promoters function in different cell growth conditions, and whether other regulator(s) are involved in expression and regulation of serA . In this study, I confirm that …
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Phenotypic Analysis of the Regulatory Role of the Leucine-Responsive Regulatory Protein (LrpPA) in Pseudomonas aeruginosa
… The leucine- responsive regulatory protein (Lrp) could be a promising target for treatment. The ortholog in <em>Escherichia coli</em> is a global regulator of metabolism and regulates many genes related to amino acid degradation, transport and synthesis. There are structural and functional …
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Role of the Leucine-responsive Regulatory Protein during growth of the bacterial corn pathogen Pantoea stewartii subspecies stewartii in the xylem environment
… Leucine-responsive Regulatory Protein (Lrp). To better understand the role of Lrp when Pss inhabits the xylem, RNA-Seq experiments comparing Pss wild-type and ∆lrp strains grown in planta were conducted to ascertain differential gene expression. The RNA-Seq data was further analyzed …
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Interaction studies of the cellular prion protein
… Recently, the 37-kDa/67-kDa laminin receptor LRP/LR was identified as the receptor for cellular PrP. Besides the in vitro interaction of PrP and LRP the binding domains on PrP and LRP were mapped in the yeast two-hybrid system. In addition, cell binding assays revealed a second HSPG-dependent …
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The role of the 37-kDa/67-kDa laminin receptor in the cellular metabolism of the prion protein
… Interaktion des 37-kDa/67-kDa Laminin-Rezeptor (LRP/LR) mit dem Prion Protein beleuchtet. Dabei konnte gezeigt werden, das beide Proteine an der Zelloberfläche von neuronalen Zellen interagieren und daß LRP/LR für die Internalisierung von rekombinantem PrPC notwending ist. Diese Internalisierung …
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Collection-and-Delivery-Points: A Variation on a Location-Routing Problem
… a variation on a location-routing problem (LRP) was created, a mixed-integer programming model called the CDP-LRP. Unlike standard LRPs, the CDP-LRP takes into account both the delivery truck route distance and the direct customer travel to the CDPs. Also, the facilities being placed are not …
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The effects of licorice root components on cognition
… extract (LRE), and whole licorice root powder (LRP) were assessed. ISL is a pure compound found in licorice root with known estrogenic activity. LRE and LRP are both complex mixtures containing ISL as well as other components. Working memory was assessed in the DSA study. Middle-aged female rats …
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Theory and application of learning automata.
… are considered and it is shown that the Lrp and Lri automata do not converge to the optimum for a non-autonomous environment. Three automata are proposed, which are designed to operate in non-autonomous environments. Their performances are compared to those of the Lrp and Lri automata. …
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Towards Improving Accuracy and Interpretability of Deep Learning based on Satellite Image Classification
… al. [1] called Layer-Wise Relevance Propagation (LRP) back propagates the resulting classification scores through the network until it reaches the input layer. The resultant scores at the input layer are called the relevance of the image and represent the contribution per pixel towards the final …
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Functional and Oncological Results after Radical Prostatectomy // Функционални и онкологични резултати след радикална простатектомия
… хоспитализирани и оперирани по методите на ORP и LRP. В дисертационния труд се извършва сравнение на пациентите в двете оперативни групи по следните показатели: възраст, PSA, тегло на простатна жлеза, средно оперативно време, интраоперативна кръвозагуба, усложнения, среден болничен престой, …
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Characterization of a mutation demonstrating a link between the lack of S-adenosylmethionine and cell division in Escherichia coli
… has been transferred via transduction to an $lrp\sp+$ background, where normal growth rates on minimal medium require the presence of 50 $\mu$g/ml L-leucine. When the leucine concentration is reduced to 25 $\mu$g/ml or less, cells fail to divide, resulting in the formation of long filaments. …
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Simulated annealing algorithm for customer-centric location routing problem
… We propose solving the location routing problem (LRP) aiming at minimizing customer waiting time with capacitated depots and vehicles. We take two approaches to solve this problem: mathematical model and heuristic algorithm. The mathematical model obtains the optimal solution, but it has a …
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