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Showing 1 to 3 of 3 for “"LPCAT2"”.

  1. Regulation of The Expression and Lysine Acetylation of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (LPCAT2) in RAW264.7 Cells

    … of the macrophage membrane phospholipid bilayer. LPCAT2 is a subtype of LPCAT that regulates inflammatory responses to infection by lipopolysaccharides and lipopeptides. LPCAT2 co-localises with TLR4 and prevents its translocation to the signalling site (lipid rafts) of macrophage membranes. The …

    plymouth Repository record for Regulation of The Expression and Lysine Acetylation of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (LPCAT2) in RAW264.7 Cells (opens in a new tab)

  2. Lysophosphatidylcholine acyltransferase-2 (LPCAT-2) & protein S-acylation in macrophage innate immunity

    … the generation of platelet-activating factor. LPCAT2 also mediates lipopolysaccharide (LPS)-induced cytokine responses in both murine and human macrophages. Investigations into the mechanism behind LPCAT2 involvement into LPS-induced cytokine responses identified that LPCAT2 translocates to …

    plymouth Repository record for Lysophosphatidylcholine acyltransferase-2 (LPCAT-2) & protein S-acylation in macrophage innate immunity (opens in a new tab)

  3. Toll-like receptor expression and signalling in rat trigeminal neurons: Consequences for oral infection and mechanisms of orofacial pain.

    … by a range of sensory neuron sub-types whereas LPCAT2 expression was confined to non-neuronal cells. Following nerve injury, the expression of LPCAT2 was induced in a small proportion of TG neurons in vitro whilst the expression of LPCAT1 remained unaltered. These results may support a role for …

    plymouth Repository record for Toll-like receptor expression and signalling in rat trigeminal neurons: Consequences for oral infection and mechanisms of orofacial pain. (opens in a new tab)