Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"LPA2 receptor"”.
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Role of the LPA2 Receptor in Protecting Against Apoptosis
… protection. In RH7777 cells lacking LPA receptors, OTP selectively protected LPA<sub>2</sub> but not LPA<sub>1</sub> and LPA<sub>3</sub> transfectants. In C57BL/6 and LPA<sub>1</sub> knockout mice exposed to 15 Gy g-irradiation, orally applied OTP reduced the number of apoptotic bodies …
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ROLE OF LYSOPHOSPHATIDIC ACID IN REGULATION OF CANCER CELL METABOLISM
… that LPA production and expression of its receptors are dysregulated in multiple human malignancies. The mechanism behind LPA-mediated tumor cell growth and oncogenesis remains poorly understood. In this thesis project I used ovarian and other cancer cells as a model system to examine the …