Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"LOV2"”.
-
Structural Basis of Signal Transduction within Environmental Sensing PAS Regulated Ser/Thr Kinases
… (<strong>PAS-A & PAS-B in hPASK; LOV1 and LOV2 in AsPhot1</strong>) N-terminal to the STK domain. In hPASK, the PAS-A domain interacts and regulates the kinase activity, whereas in <em>As</em>Phot1 LOV2 domain is the regulator of kinase function. hPASK is an important regulator of cellular …
-
Structure-function analysis of phototropin receptor kinases
… mapped. Additionally, the importance of LOV2 and the Jalpha-helix as components of the phototropin receptor activation are confirmed. The implications of such findings for our understanding of phototropin autophosphorylation are discussed. LOV domains bind flavin mononucleotide as a …
-
Development of an Optogenetic Toolkit for the Interrogation of T cell Signalling Dynamics
… in this work utilise the blue light-responsive LOV2 photo-domain from the common oat A. Sativa, which is the foundation of the both the ‘LOVTRAP’ and ‘TULIPs’ optogenetic toolkits. T-cell antigen receptor (TCR) microclusters arise early during the interaction between T cells and antigen …
-
Investigation of phototropin blue light receptor function and signalling in arabidopsis
… to light. A transgenic line overexpressing the LOV2-kinase region of phot1 demonstrates that phot1 autophosphorylation is not the primary signalling event involved in phot1-mediated responses to light and shows that the truncated version of phot1 is sufficient to complement most phot1-mediated …