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Showing 1 to 4 of 4 for “"LIPUS"”.
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Characterization and Implementation of Low Intensity Pulsed Ultrasound as a Tool to Apply Physical Load to Scaffolds and Bone Cells for Fracture Repair
… delayed unions. Low Intensity Pulsed Ultrasound (LIPUS) has been approved by the FDA to treat fresh fractures since 1994 and non-unions since 2000 and is an attractive treatment option because it is non-invasive. The mechanism by which it works, however, is not well understood; what is known is …
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The effect of bone anabolic stimuli on human osteoblast to osteocyte transition.
… Secondly, low intensity pulsed ultrasound (LIPUS), an emerging therapy for osteoporosis and fracture repair, was also assessed for its effects on NHBC differentiation into OY. We hypothesised that each of these stimuli would exert a proanabolic effect on NHBC differentiation, promoting their …
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Trabecular Calcium Phosphate Scaffolds for Bone Regeneration
… application of low intensity pulsed ultrasound (LIPUS) or fluid perfusion further stimulated cell-scaffold hybrids for short and long term in vitro study. Additionally, an animal model was characterized using the scaffolds for the repair of a segmental defect in the canine mandible.Study of the …
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Calibration and Validation of an in Vitro Ultrasound Device to Deliver Targeted Thermal Enhancement of hMSC Osteogenesis
… and localized. Low-intensity pulsed ultrasound (LIPUS) has been proven in clinical studies to increase the rate of healing of non-union fractures in rat models, primarily through the mechanical component, and referring to LIPUS itself as a way of producing mechanical stress. LIPUS itself is …