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Showing 1 to 20 of 484 for “"LIM"”.
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The development of the LIM regression model
Not available
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Molecular and Cellular Mechanisms of LIM Protein Mechanotransduction
… cytoskeletal mechanotransduction is achieved is limited. LIM domain proteins are a superfamily of cytoskeleton-associated proteins involved in cytoskeletal remodeling and transcriptional regulation, but how mechanical forces modulate their functions is unclear. Here, I employed an …
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Nukleäre Funktionen des Muscle LIM Proteins in der Herzmuskelhypertrophie
Bei verschiedenen pathologischen Zuständen des Herzens wurde bereits eine vermehrt nukleäre Lokalisation des bislang vornehmlich als Zytoskelett-Protein bekannten MLP beobachtet. In der vorliegenden Arbeit wurde die Lokalisation sowie die Expression von MLP nach Koronarligatur als einem Modell für …
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Role of the Ajuba LIM Proteins in Epithelial Growth Regulation
The mammalian Ajuba LIM proteins: Ajuba, LIMD1, WTIP) are cytosolic adapter proteins recruited to nascent epithelial adherens junctions, where they are thought to contribute to junctional assembly and/or stability. They also shuttle into the nucleus acting as corepressors of the Snail family of …
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The arcane and the ordinary: an exploration of patriarchy and the postcolonial in the writing of Beth Yahp, Catherine Lim and Shirley Geok-Lin Lim
… examines the work of Beth Yahp, Catherine Lim and Shirley Geok-lin Lim. Particular emphasis is given to four texts. The first is Beth Yahp's The Crocodile Fury, the second is Catherine Lim's The Bondmaid, the third is Catherine Lim's The Teardrop Story Woman, and the final text is Shirley …
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Negative Regulation of the Hippo Pathway by the Ajuba LIM Proteins
… work from our lab has identified the Ajuba LIM proteins as novel negative regulators of the Hippo pathway in both Drosophila and mammals. However, the mechanism by which the Ajuba LIM proteins prevent Hippo pathway activity is not known. Using contact inhibition of proliferation as a …
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Suitability of Quantized DEVS-LIM Methods for Simulation of Power Systems
… methods namely the Latency Insertion Method (LIM) and Linear Implicit Quantized State (LIQSS)method. This technique is rigorously evaluated across a diverse array of systems and scenarios, with the aim of unearthing nuanced insights into its respective functionalities.</p> <p>The research …
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The Role of LIM Kinase 1 and its Substrates in Cell Cycle Progression
<p>LIM Kinase 1 (LIMK1), a modulator of actin and microtubule dynamics, has been shown to be involved in cell cycle progression. In this study we examine the role of LIMK1 in G1 phase and mitosis. We found ectopic expression of LIMK1 resulted in altered expression of p27Kip1, the G1 phase Cyclin …
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Modifikation des Hypertrophie-Phänotyps der Myosin-Bindungs-Protein-C defizienten Maus durch Muscle-LIM-Protein
… defizienten Maus durch Muscle-LIM-Protein Von einer Herzinsuffizienz sind etwa 3 % der Menschen in den alten Bundesländern betroffen. Ursächlich liegt oft eine genetische Veränderung in Funktionsproteinen vor, zu denen das Myosin-Bindungs-Protein-C (MyBPc) und das …
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Co-factors of LIM-HD transcription factors in neural development and axon pathfinding in zebrafish
… block motor axon pathfinding by interfering with LIM domain transcription factor signaling. LIM homeodomain proteins (LIM-HDs) are an important class of transcriptional regulators and involved in neural development as well as neuron fate decision in vertebrates. DD domain dimerization of CLIM …
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Application of the latency insertion method (LIM) to the analysis of large circuit interconnect networks
… based on the latency insertion method (LIM) to the analysis of circuit interconnects. Special attention is devoted to addressing the issues that arise in very large networks such as on-chip signal and power distribution networks. We demonstrate that the LIM has the power and flexibility …
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Untersuchung des kardialen LIM-Domänen Proteins FHL2 im menschlichen Myokard : Rolle von FHL2 bei der Herzinsuffizienz
… nach Kofaktoren des Androgenrezeptors wurde ein LIM-only Protein identifiziert, daß als FHL2/Slim3/DRAL mit unbekannter Funktion beschrieben war (Müller et al., 2000). Da Androgene zu Myokardhypertrophie führen können (Marsh et al., 1998), bestand die Aufgabe darin, die pathophysiologische …
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A four-and-a-half LIM protein FHL2 acts as a coactivator for the Wilms' tumor suppressor WT1 during gonadal differentiation
An essential step during sex determination is the maintenance of the Müllerian duct in females which gives rise to oviduct, uterus and the upper part of vagina and its regression in males caused by the expression of Müllerian inhibiting substance (MIS). The Wilms' tumor suppressor (WT1) and the …
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Latinx fifth-grade student perceptions of their experiences in a leadership skills and social-emotional learning program : a phenomenological study.
… context that employed the Leader in Me (LiM) program in school to provide leadership development opportunities. The focus on student experiences within the LiM program showed how leadership development had the potential to address opportunity gaps. It was crucial to evaluate how the LiM …
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Extracting frequency domain network parameters using the latency insertion method
… algorithm called the latency insertion method (LIM). LIM is a finite difference formulation comparable with current industry standard circuit simulators, with several advantages, namely linear numerical complexity. In this work, the theoretical underpinnings of LIM and the tool are established. …
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A fast multi-purpose circuit simulator using the latency insertion method
… techniques. The latency insertion method (LIM) has recently emerged as an efficient approach for performing fast simulations of very large circuits. By exploiting latencies in the circuit, LIM is able to solve the voltages and the currents in the circuit explicitly at each time step. This …
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Uniform L¹ behavior for the solution of a volterra equation with a parameter
… it is necessary that (-lnt)a(τ)∈L¹(0,1) and lim sup <sub>τ→∞</sub> (τθ(τ))²/φ(τ) <∞ where â(τ)=∫<sub>0</sub><sup>∞</sup>e<sup>-iτt</sup>a(t)dt=φ(τ)-iτθ(τ) (φ,θ both real). We obtain sufficient conditions for (F) to hold which involve φ and θ (See Theorem 7). Then we look for direct …
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RESISTANCE AND SOCIAL CONFLICT DURING AND AFTER THE JAPANESE OCCUPATION OF MALAYA AND SINGAPORE IN THE NOVELS OF CHIN KEE ONN, NOEL BARBER AND LIM THEAN SOO
… (1961); Noel Barber - Tanamera (1981)~ and Lim Thean Soo – Destination Singapore (1976), The Towkay of Produce Street (1991) and short stories about the Pacific War are explored and analysed for their portrayal of the historical experience of this period. A comparative approach will be …
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