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Showing 1 to 2 of 2 for “"LHX3"”.
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Molekulargenetische Untersuchungen zur Rolle des humanen LHX3-Gens bei der menschlichen Hypophysenentwicklung
LHX3 is a LIM-HD protein and plays an important role in the organagenesis of the piitary gland as demonstrated by knock mice experiments. Genetic studys in patients with combined pituitary deficency provides apart from knock out models a tool to improve the knowledge about the transcriptional …
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DELETION OF THE Foxo1 GENE IN MOUSE PITUITARY GLAND AND THE EFFECTS ON SOMATOTROPE DIFFERENTIATION AND FUNCTION
… deficiency (CPHD). Defects in genes such as LHX3, LHX4, RPX, PROP1, and PIT1 are known to contribute to CPHD in humans. FOXO1 is a member of a large family of forkhead transcription factors. FOXO1 is expressed in various tissues where it functions to regulate metabolism, maintenance of cell …