Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 70 for “"LDL-cholesterol"”.
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Microarray Analysis Identifies Novel Cholesterol Regulated Genes, Including Pcsk9 Which Regulates LDL Receptor Function and LDL Cholesterol Levels
<p>Precise regulation of cholesterol levels is necessary for survival of individual cells and the normal functioning of multicellular organisms. Many of the genes important in these processes are regulated at a transcriptional level by the sterol regulatory element binding proteins (SREBPs) and …
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Lipid acquisition by apolipoprotein A-I in ER and Golgi compartments of primary mouse hepatocytes
… upon export from the cell. Intracellular LDL-cholesterol lipidation of apoA-I is absent, with rapid cholesterol accumulation at the plasma membrane. De novo synthesized cholesterol was able to lipidate apoA-I intracellularly to a small but significant level. In hepatocytes lacking ABCA1, …
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The Copper Status of Vegetarian and Non-vegetarian Men
… by atomic absorption spectroscopy. Plasma cholesterol, triacyclglycerols, HDL cholesterol, LDL cholesterol VLDL cholesterol were also determined. Twenty-four hour recalls and three-day food records were obtained to determine copper, zinc, energy, protein, fat, fiber, saturated fat, oleic …
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Prevalence of dyslipidaemia among adults in Africa: a systematic review and meta-analysis
… prevalence of elevated concentrations of total cholesterol, LDL cholesterol, or triglycerides, or low concentrations of HDL cholesterol in adults residing in African countries. We excluded reports on Africans living outside Africa, studies of individuals selected on the basis of existing …
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The Molecular Mechanism Of The Gwas Association Of The Slc22a1 Locus With Metabolic Traits
… acylcarnitine and low-density lipoprotein (LDL) cholesterol levels, suggesting previously unknown roles of SLC22A1 in the regulation of acylcarnitine and cholesterol metabolism. In this study, we aimed to investigate the molecular mechanism by which SLC22A1 and its variants alter plasma …
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Die effek van inoefening op enkele koronêre risikofaktore en hulle onderlinge verwantskap by Suid-Afrikaanse bestuurslui
… biochemical analysis included measures of total cholesterol, triglycerides, HDL-cholesterol and glucose. The LDL-cholesterol and TC/HDL-ratio values were calculated. Blood pressure measurements and a physical work capacity170 test on a Monark cycle ergometerwas also done on each of the …
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Efavirenz pharmacogenetics and metabolic toxicity in black South Africans
… CYP2B6 slow metaboliser genotype and total cholesterol (β = 13.78, p = 0.003), LDL cholesterol (β = 15.89, p = 0.008) and HDL cholesterol (β = 24.78, p = 0.002). These associations remained significant in multivariate analyses adjusting for age, sex, weight, baseline CD4 cell count and viral …
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Impatto del profilo lipidico sulla malattia aterosclerotica in due differenti coorti di pazienti ad alto rischio cardiovascolare
… three principle pathogenic phenotypes: pure hypercholesterolemia [a very increased amount of low-density lipoprotein (LDL) cholesterol], atherogenic dyslipidemia [combined increased amount of LDL cholesterol and tryglicerides (TG)] and pure hypertrygliceridemia (a very increased amount of TG) (2). …
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Association of blood lipids, atherosclerosis and statin use with dementia after stroke
… lipids showed that low-density lipoprotein (LDL) cholesterol was associated with increased risk of post-stroke dementia (adjusted hazard ratio [aHR] 1.29, 95% confidence interval [CI] 1.14-1.47, per one log-mmol/L increase), with a linear increasing trend in the risk across quintiles and …
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The Effect of a 20-25 calories % Fat Diet on Plasma Thromboxane B₂ Levels in Human Subjects
… weeks when compared with initial values. Serum cholesterol, HDL cholesterol, and LDL cholesterol were significantly decreased over the four-week period. No significant changes were observed in serum triglycerides.</p>
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Altered feeding pattern:its effect on selected blood lipids in humans
… for kilocalorie, total fat, saturated fat, and cholesterol intake. Mean intake of cholesterol was found to be within a desirable range. Mean intake of total fat and saturated fat were noted as exceeding desirable values. Blood samples were collected from each subject following a two week …
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The Effects of Consumption of California Dried Mission Figs on Serum Lipid Concentrations in Hyperlipidemic Adults
<p><strong>Background</strong>: The National Cholesterol Education Program and American Heart Association have recommended the use of functional or cholesterol-reducing foods, some categories of which include viscous or soluble fibers, soy protein, plant sterols, and nuts, as aids to reduce serum …
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The effects of fish oil versus corn oil on subjects with hyperlipidemia and type II, noninsulin dependent diabetes mellitus
… lowered plasma very low density lipoprotein (VLDL)-cholesterol (p<0.007), plasma triglycerides (TG) (p<0.015), and plasma VLDL-TG (p<0.02) were found in subjects consuming fish oil supplements than in those consuming corn oil. In addition, total plasma TG was decreased by 22 percent (p<0.05) …
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Lipoprotein Lipase in the Arterial Wall: Regulation by Dietary Fatty Acids
Arterial LDL deposition is a key step in initiating atherosclerosis. Saturated fat (SAT)-enriched diets increase arterial LDL deposition, total and selective LDL-cholesterol uptakes, and arterial lipoprotein lipase (LpL). Because consumption of n-3 fatty acids (FA), such as EPA and DHA, potentially …
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Heart-focused Anxiety and Cardiac Treatment Adherence
… whether heart-focused anxiety predicted healthy LDL, HDL and blood pressure levels above and beyond the influence of demographic variables, other known predictors, and general anxiety. None of the CAQ subscales significantly predicted adherence, but effect sizes were large enough to warrant …
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The effects of using cottonseed oil versus corn oil as part of an overall dietary strategy to increase vitamin E intake in healthy participants
… E intake. There were no significant changes in cholesterol levels. There was however, a significant change in triglyceride level, with the corn oil group showing an increase and the cottonseed oil group showing a decrease. The change in total cholesterol trended downward in the corn oil group …
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Low Density Lipoprotein Cholesterol Decreases in Fifth-grade Students Following the Teen Taught KidQuest Program
… Fun Packs and Take 10! Activities) groups. Total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides, and BMI were measured at baseline, completion of the program (six months), and at 12 months. <br /><strong>Results:</strong> Ninety-one subjects, mean age …
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The impact of social deprivation on development and progression of diabetic kidney disease
… A1c (HbA1c), eGFR and low-density lipoprotein (LDL) cholesterol across socioeconomic categories. I then used linear and logistic regression models to examine the association between deprivation and rate of decline in renal function. Results The main findings in this thesis are: a) The literature …
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Biochemical markers of hypertension and chronic renal failure in a Gulf Arab population of the United Arab Emirates
… ET-1 and lower high-density lipoprotein- (HDL)-cholesterol. Further, both SBP and DBP weresignificantly correlated with age, BMI. NEFA, ET-1 and log insulin and TG and negatively with HDL-cho!esterol. The independence of associations between blood pressure and ET-1 or HDL-cholesterol and ET-1 …
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The New Role of Proprotein Convertase Subtilisin/Kexin Type 9: A Connection of Proprotein Convertase Subtilisin/Kexin Type 9, Apolipoprotein B, and Autophagy
<p>Plasma low-density lipoprotein (LDL) levels are positively correlated with the incidence of coronary artery disease. In the circulation, the plasma LDL clearance is mainly achieved by the uptake via LDL receptor (LDLR). Proprotein convertase subtilisin/kexin type 9 (<em>PCSK9</em>) is a newly …
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