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Showing 1 to 1 of 1 for “"LDL receptor degradation"”.

  1. Characterization of PCSK9-mediated LDLR Degradation in Hepatic and Fibroblast Cells

    Nguyen, My-AnhUniversité d'Ottawa / University of Ottawa2013

    … subtilisin/kexin type 9 (PCSK9) mediates degradation of low-density lipoprotein receptors (LDLR) indicates a critical role in LDL metabolism. PCSK9 is a secreted protein that binds to the epidermal growth factor-like (EGF)-A domain of LDLR and directs the receptor for degradation in …

    ottawa-retro Repository record