Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"LDHB"”.
-
유전자 적중법을 이용한 조건적 LDHB 유전자 삭제 마우스 제작
… activity. But LDH activity is inverse amounts of LDHB. So we want make the condition of increased LDHA activity without LDHB in the cell. In this study, we designed a targeting vector about LDHB gene used by LDHB genome(mouse). And then, this targeting vector insert into the ES cell. Then targeted …
-
Regulation of mitochondrial respiration by LDHB suppression in hepatoma cell lines
… from two types of subunit with LDHA and LDHB gene product. Recently, we reported that LDH5 isoenzyme formed by LDHB suppression is involved in increased glycolytic lactate production and mitochondrial respiratory defects in hepatoma cells. In this study, we aimed to investigate how LDHB …
-
Early onset of age related hearing loss in LDHB knock out mouse
… metabolism study of Age-related hearing loss in LDHB knockout mice. In response to deletion of LDHB gene in mouse caused early onset of age related hearing loss, as increase of high frequency threshold, hair cell death, which are the typical features of Age-related hearing loss. We investigate …
-
Evolution Of Lactate Dehydrogenase Genes In Primates, With Special Consideration Of Nucleotide Organization In Mammalian Promoters
… (LDH). The two primary LDH genes, LDHA and LDHB, confer different rates of substrate turnover to the LDH enzyme, and these rates lend to the argument that LDHA supports anaerobic while LDHB supports aerobic metabolism. The expression profiles of these proteins shifted during primate …
-
Durch Sirolimus induzierte frühe Veränderungen des Proteoms und Phosphoproteoms in humanen T-Lymphoblasten
… zeigte fünf vermehrt (ECHB, PSB3, MTDC, LDHB, NDKA) und vier vermindert (EHD1, AATC, LMNB1, MDHC) exprimierte Proteine. Neun dieser unterschiedlich regulierten Proteine/Phosphoproteine (TCPQ, TBA1B, VIME, HNRPD, ENPL, ECHB, PSB3, LDHB, LMNB1) stellten sich über das Bindeprotein YWHAZ als …