Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"LC3-interacting region (LIR) motif"”.
-
Probing the protein homeostasis mechanisms in long-lived naked mole-rats
… conditions of mild ER stress. In Chapter 5, LC3B turnover and transcriptional changes of autophagy markers under rapamycin (RA) and chloroquine (CQ)-treated conditions were monitored in an NMR skin fibroblast cell line, where the sensitivity of the NMR skin fibroblasts to CQ, when compared to …
-
Discovering LC3-interacting region (LIR) motifs in hemorrhagic fever viruses: Implications for host autophagy and viral replication.
… factor of RVFV and we discovered four novel LC3-interacting region (LIR) motifs within NSs (NSs1-4), indicating that NSs interacts with LC3, the host key autophagy protein. Autophagy is a cellular process that can act anti-virally by enhancing immune responses and promoting viral degradation, …