Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"LC-UV"”.
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Characterizing Modified Nucleosides in RNA by LC/UV/MS
… modified nucleosides in RNA using optimized LC/MS methods of analysis. This method was shown to be sufficient for characterizing changes in the abundance of modified nucleosides as a function of varying cellular conditions and can be used to explore the dynamics of RNA modification. These …
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Development of novel extraction and separation methods for the determination of anthracyclines and taxanes simultaneously from biological matrices
… The first method employed the use of on-line SPE-LC-UV and this method was then transferred to a mass spectrometric detector for more sensitive monitoring of the drugs. The on-line SPE-LC-MS assay did result in lower limits of detection and was fully automated. The entire method of extraction, …
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Development and application of novel approaches to quantitate therapeutic drugs in human blood
… was achieved using solid phase extraction and LC-UV analysis. The main challenge was developing a low cost assay to detect the drugs within a clinically relevant concentration range using standard chromatography equipment in order to make it applicable to resource-limited settings, in …
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Analysis and characterisation of an acylphosphine oxide photoinitiator
Photoinitiators play a key role in UV-curable systems by generating the reactive species, free radicals, ions or molecule which initiate the polymerisation of the multifunctional monomers and oligomers. This research involves the study of the hydrolytic and photolytic stabilities of two important …
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Analysis of Nucleosides and Nucleotides in Milk and Infant Formula
… a C18 stationary phase with gradient elution, UV detection, and quantitation by an internal standard technique. A single-laboratory validation was performed, with recoveries of 92–101% and repeatability of 1.0–2.3%. An extension study demonstrated the expansion in scope to a wider range of …
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Supercritical Fluid Extraction Directly Coupled with Reversed Phase Liquid Chromatography for Quantitative Analysis of Analytes in Complex Matrices
… Reversed Phase Liquid Chromatography (HP-RPLC), and to explore its ability for quantitative analysis of analytes in different matrices. First, a simple interface was developed via a single one six-port injection valve to connect the SFE and LC systems. A water displacement method was …