Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"LASV"”.
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Elucidating the Immunogenicity and Protective Immune Response of a Trivalent Vaccine for Sudan Ebola, Marburg, and Lassa Fever Viruses
… Ebola (SUDV), Marburg (MARV), and Lassa fever (LASV) viruses cause acute, severe haemorrhagic fevers resulting in high morbidity and mortality in overlapping regions of Africa. Despite millions of individuals in Africa being at risk of contracting an infection from one of these viruses, …
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ANIMAL MODELS FOR BEHAVIORAL CHANGES OR HEARING LOSS UPON ACUTE VIRUS INFECTIONS
… gyrus and thalamus. In the Stat1-/- model of LASV infection, I found that 100% of survivors developed hearing loss post-infection, which correlated with severe damage to the cochlear nerve and CD3 positive staining in the spiral ganglion, organ of corti, and scala tympani. This same damage was …
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Sphingomyelinases and Lysosomal Trafficking in Ebolavirus Entry
… encoated with either vii EBOV, Lassa virus (LASV), or Venezuelan Equine Encephalitis virus (VEEV) surface glycoproteins were incubated with cells treated with ASM inhibitors. EBOV GP pseudotyped viruses were more sensitive to ASM inhibition, suggesting a GP-specific role for ASM in entry. …