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Showing 1 to 2 of 2 for “"LAMA4"”.

  1. Molecular Determinants of Tumor Re-Initiation in Breast Cancer

    … Transcriptomic profiling revealed a set of genes–LAMA4, FOXQ1, and NAP1L3–that were expressed at greater levels in tumorigenic-enriched derivatives relative to their parental populations. These genes were also expressed at greater levels in independently derived metastatic populations. All three …

    rockefeller Repository record for Molecular Determinants of Tumor Re-Initiation in Breast Cancer (opens in a new tab)

  2. Defining The Cooperation Between Mhc-I and Mhc-Ii Neoantigen-Driven T Cell Responses to Develop Effective Personalized Immunotherapies

    … point mutation in the Laminin alpha subunit-4 (Lama4) and the MHC-II neoantigen was formed by an N710T point mutation in Integrin beta-1 (Itgb1). Anti-CTLA-4-treated mice bearing the Parental Y1.7 melanoma displayed progressive tumor growth, whereas the modified Y1.7 line expressing mLama4 and …

    uthsc Repository record for Defining The Cooperation Between Mhc-I and Mhc-Ii Neoantigen-Driven T Cell Responses to Develop Effective Personalized Immunotherapies (opens in a new tab)