Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"L-type Channels"”.
-
cAMP and Calcium Interactions in Endocrine Cells
… test modulation of calcium influx through the L-type calcium channel with PDE inhibitors. cAMP analogs were used to determine cAMP molecular targets. 8-cpt-cAMP initiated an Epac mediated pathway and had strong effects on calcium influx in the cell; suggesting, a relatively strong cAMP target. …
-
The effect of cis-5,8,11,14,17-eicosapentaenoic acid upon the contractile mechanisms linked to calcium influx and the mobilisation of intracellular calcium in aortic smooth muscle
… calcium influx through receptor-operated channels, supporting a recent suggestion by Asano et al (1997). Consistently, EPA decreased noradrenaline-induced contractures in aortic tissue, in support of previous reports (Engler, 1992b). The observed effect of EPA on cell contractions to KCl …
-
Calcium-dependent mechanisms in the chicken retina
Multiple classes of retinal amacrine cells use L-type Ca2+ channels to mediate synaptic transmission. I have used whole cell voltage clamp recordings from primary cultures of amacrine cells to investigate the regulation of these channels. In this study, I show that inhibiting mitochondrial calcium …
-
Effects of endotoxin-induced inflammation on glucose metabolism and contractility of the rat heart in vivo and in vitro
… calcium influx through voltage-sensitive Ca2+- channels (L-type channels) was measured. It was found that an incubation of these cells in vitro with LPS (1 µg/ml) for 1-2 h reduced the calcium current by 50%. This effect was prevented by co-incubation with cyclooxygenase inhibitor indomethacin …
-
Biochemical differences in the modes of synaptic vesicle release between control and streptozotocin-induced diabetic rats and possible relationship to changes in behaviour
… and thus the role of voltage-gated calcium channels (VGCCs) was studied. Blockade of L-type (but not N-and P-type) VGCCs switch K&R exocytosis to FF mode in control terminals, indicating that such channels contribute to the calcium increase that induces K&R mode. These results (for the first …