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Showing 1 to 20 of 20 for “"L-glutamic acid"”.
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Synthesis and Characterization of Novel Polyethers and Polypeptides for Use in Biomedicine and Magnetic Resonance Imaging
… yielding well-controlled nanoparticles. Poly(L-glutamic acid) is comprised of naturally occurring L-glutamic acid repeating units that are linked together with amide bonds. In this research, we have prepared magnetic block ionomer complexes based on poly(ethylene oxide)-b-poly(L-glutamic acid) …
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The Fate of Folic Acid and Related Compounds in the Rat
… folates. At doses of 22 and 320ug of pteroyl-L-glutamic acid/ kg, 50 and 25% respectively was absorbed, With doses of 320ug of [214-C]pteroyl-L-glutamic acid/kg, radioactivity was detected in the peripheral circulation 10 minutes after administration. Pteroyl-L-glutemic acid was absorbed without …
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The synthesis and pharmacological evaluation of quisqualic acid and some novel excitatory amino acid mimetics
L-Glutamic acid and L-aspartic acid are believed to be the principal initiators of excitatory synaptic neurotransmission in the mammalian central system. A number of molecules of either natural or synthetic origin have been identified as possessing agonist or antagonist properties at glutamate …
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Efforts Toward the Total Synthesis of Asparagamine A
… asparagamine A in enantiospecific fashion from L-glutamic acid has been identified. This approach utilizes an intramolecular azomethine ylide 1,3-dipolar cycloaddition reaction as the key step. Generation of the azomethine ylide species is achieved via sequential vinylogous amide O-sulfonylation …
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Transport of Folic Acid and Related Compounds Across the Small Intestine
The intestinal transport of folic acid (pteroyl-L-glutamic acid) was investigated using in vitro preparations of rat jejunum. It was established that folic acid is accumulated in the gut wall and transported into the serosal compartment by a saturable mechanism. The kinetic parameters and the …
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Μελέτη των θέσεων δέσμευσης του L-γλουταμικού οξέος σε φυσιολογική και ατροφική ανθρώπινη παρεγκεφαλίδα: Συμβολή στη μελέτη της ελαιογεφυρο-παρεγκεφαλιδικής ατροφίας
… CI⁻ dependent and -independent conditions for L-glutamic acid with Kd values in the order of 150Χ10⁻⁹Μ. Hill plots of these data were linear with Hill coeficient equal to 1.0. Chloride ions provoked a significant increase of L-glutamate binding, with ratio of Cl⁻-dependent/-independent binding …
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The identification of novel cys-loop receptor genes in Dirofilaria immitis
… forms a monosodium L-glutamate (MSG) and L-glutamic acid sensitive homomeric channel, whereas the Dim-GLC-2/Dim-GLC-4 heteromeric channel shows reduced MSG current amplitude. The Dim-LGC-49 homomeric channel is responsive to cholinergic compounds. Homology modelling of homomeric channels …
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Influence of impurities on the crystallisation of pharmaceutical materials
… be used to produce a pure polymorphic form of L-glutamic acid and whether or not enthalpy measurements were an advantage of this reactor for monitoring the crystallisation. Particles obtained from crystallisation experiments in this reactor were analysed using in-situ Raman spectrometry (for …
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The effect of high-polyphenol sumac on food intake in younger and older adults, using sensory and appetite analysis
… it can be hypothesised that sumac, containing glutamic acid, in addition to its high antioxidant and polyphenol content as a potential natural flavour enhancer, might also increase appetite among older adults. This PhD study aimed: (1) to determine the antioxidant activity (mol/ L), polyphenol …
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Investigation of batch and continuous crystallisation processes using non-invasive Raman and acoustic emission spectrometries
Crystallisation of L-glutamic acid (LGA) and D-mannitol were studied in batch and continuous reactors using non-invasive, wide area illumination Raman spectrometry to identify the nucleation point, monitor crystal growth and identify the polymorphs formed. Non-invasive broadband acoustic emission …
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STUDIES ON NATURAL AND EDIBLE BIOPOLYMERS. ISOLATION, CHARACTERIZATION AND CHEMICAL MODIFICATIONS OF POLY(Γ-GLUTAMIC ACID) (Γ-PGA) FROM BACILLUS SUBTILIS
Poly(γ-glutamic acid) (γ-PGA) is a unusual anionic, water-soluble homopolyamide composed of D- and/or L-glutamic acid monomers, connected by amide bonds between α-amino and γ-carboxyl groups, mainly produced by Gram-positive bacteria of the genus Bacillus. γ-PGA is hygroscopic and water-soluble; in …
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Bacterial poly-gamma-Glutamic Acid (y-PGA) - a promising biosorbent of heavy metals
Poly-γ-glutamic acid (γ-PGA) is a biopolymer made up of repeating units of L-glutamic acid, D-glutamic acid or both. γ-PGA is water soluble, non-toxic and biodegradable, and can be used safely in a variety of applications that are increasing rapidly. This study investigated the production of HMW …
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Synthesis and Surface Characterization of Silica-Polypeptide Composite Particles
… hydrogen bromide yielding silica-PLGA (poly(L-glutamic acid)) particles. The hydrodynamic radii and zeta potential were studied as function of pH. The silica-PLGA composite particles appear extended and negatively charged at high pH and compact and neutral at low pH. This can be attributed to …
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Adsorption of Novel Block Copolymers for Steric Stabilization and Flocculation of Colloidal Particles in Aqueous Environments
… for brush-forming block copolypeptides. Poly-L-(glutamic acid) (GLU) and poly-L-(aspartic acid) (ASP) were found to adsorb on positively charged and nearly neutral Al2O3, while the GLU did not adsorb on negatively charged SiO2. Poly-L-proline (PRO) adsorbed only slightly on the alumina, but …
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BIOINSPIRED POLYAMIDOAMINES AS INNOVATIVE FLAME RETARDANTS FOR CELLULOSIC FABRICS
… 1. Polyamidoamines derived from natural a-amino acids as effective flame retardants for cotton fabrics; 2. Study of the polyamidoamine decomposition products upon heating; 3. Phosphorous-sulphur-based polyamidoamines as flame retardants for cotton fabrics; 4. Study of the synergism between …
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Control of polymorphism in continuous crystallization
… polymorphic compounds. Using the monotropic L-glutamic acid as the model compound, two temperature regimes each with distinctive kinetic and thermodynamic characteristics were identified. It is found that at high temperatures, the polymorph dynamics is mediated by the relative thermodynamics of …
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The role of γ-polyglutamic acid in a circular economy: cost-effective production and wide-ranging applications of a bio-derived, biodegradable, and nonimmunogenic biomaterial
… as backbones of biodegradable constructs. Poly-γ-glutamic acid (γ-PGA) is an anionic pseudo polypeptide produced by several microorganisms, especially members of the Bacillus species. γ-PGA is synthesised through several enzymes and complexes which racemise and polymerise L- glutamic acid or D- …
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Dual biopolymer production and separation from cultures of Bacillus spp.
… glucose, 1.5 g/L yeast extract, 2.4 g/L citric acid, 32 g/L glutamic acid and 12 g/L ammonium sulphate was identified as the dual polymer production medium. Using an inoculum medium different from the production medium proved to have a positive effect on the production. Consequently, 1 g/L …
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Selection of bacterial species from wastewater for potential production of poly (γ-glutamic acid): isolation, characterisation and growth kinetics
… such as the production of alcohols, organic acids and polymers. The nutrient loads in municipal wastewaters are dilute, but add up to significant daily loads because of the massive volumes generated in urban populations. The effluent of most wastewater treatment plants in South Africa is …
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Doppelthydrophile Blockcopolymere als Mineralisationstemplate
Die vorliegende Arbeit beschäftigt sich mit der Synthese und den Eigenschaften von doppelthydrophilen Blockcopolymeren und ihrer Anwendung in einem biomimetischen Mineralisationsprozeß von Calciumcarbonat und Bariumsulfat. Doppelthydrophile Blockcopolymere bestehen aus einem hydrophilen Block, der …