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Showing 1 to 20 of 95 for “"L-Arginine"”.
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L-arginine overproduction in Corynebacterium glutamicum ATCC 13032
… and L-threonine. With the exception of Larginine, the biosynthesis and regulation of most of these compounds in this bacterium are relatively well characterised in the literature. The research presented here focuses on improving our understanding of the regulation of L-arginine …
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IMPACT OF L-ARGININE TRANSPORTATION ON MYELOID-DERIVED SUPPRESSOR CELL FUNCTION
… MDSC suppressive activity is the metabolism of L-Arginine (L-Arg) by Arginase 1 (ARG1) and nitric oxide synthase 2 (NOS2). Therefore, we hypothesized that restricting MDSC uptake of L-Arg is a critical control point to modulate their suppressor activity. To this end, we have identified the …
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The Crystal Structure Analysis of L-Arginine Dihydriodide and L-Tyrosine Hydriodide
Made available in DSpace on 2014-12-09T17:35:41Z (GMT). No. of bitstreams: 1 6706727.pdf: 5650685 bytes, checksum: 95da4d30abdc8bb3fabfc474690065ba (MD5) Previous issue date: 1966
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AN HEALTHY DIET AND AN HEALTHY FOOD ADDED WITH L-ARGININE: BIOAVAILABILITY AND BENEFICIAL EFFECTS
Background The use of L-Arginine as food supplement to a normal diet, in relatively large doses, has been proved to have a salutary effect on cardiovascular diseases and glucose metabolism. L-Arginine was found to be bio-available and effective in the prevention of impairment of glucose metabolism …
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Studies on the Synthesis and Metabolism of 1-(l-Arginine)-1-Deoxy-D-Fructose and the Possible Mutagenic Effects of Maillard Reaction Mixtures
The absorption and metabolism of fructose-arginine was examined in weanling rats. Fructose-arginine is the Amadori compound resulting when dextrose reacts with arginine during the Maillard reaction. Fructose-(U-('14)C)-arginine and L-(U-('14)C)-arginine were administered by stomach intubation. …
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Sensory Characteristics and Optimization of a Low-Sodium Salt Formulation and its Food Application
… to be used in salt substitute formulations. L-Arginine has been reported to have bitterness masking properties. No research has yet been conducted to investigate the effects of KCl and L-Arginine on the perception of saltiness and bitterness in the mixture of NaCl, KCl, and L-Arginine. To …
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FITSelect: An Invention to Select Microbial Strains Maximizing Product Formation from a Single Culture Without High-Throughput Screening
… a natural feedback inhibition mechanism in the L-arginine production pathway to select strains (transformed with a random genomic library) that can over-produce L-arginine in E. coli DH10B. With FITSelect, the cell can thrive in the growth competition assay when L-arginine is over-produced (i.e., …
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Nitric Oxide Involved in the Leptin Effect on Food Intake in Broiler and Leghorn Chickens
… studied the effect of leptin combined with L-arginine on the food intake in broilers. Intracerebroventricular (ICV) administration of human recombinant leptin injection decreased (P=.01) food intake from 15 to 150 minutes compared to the control group treated with artificial cerebrospinal …
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Immunopathogenic mechanisms of non-healing cutaneous leishmaniasis caused by Leishmania amazonensis infection
… (mCAT-2B), a key transporter for L-arginine. Although a clear upregulation of mCAT-2B and L-arginine transport was detected, no measurable iNOS or arginase activities were observed in IFN-g-treated, infected MFs. These data suggest an involvement of a novel L-arginine usage …
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THE EFFECTS OF ORAL ARGININE ON ITS METABOLIC PATHWAYS IN SPRAGUE-DAWLEY RATS
Oral arginine supplements are commonly used by the public for their presumed nitric oxide potentiating and vasodilatory role. However, there is a lack of clarity on the physiological impact of oral arginine on its metabolic pathways in the human body. As a versatile molecule, arginine is …
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Blood-CNS transport mechanisms in pathophysiology and drug delivery
… was split into two main parts: <br/><br/>1. L-arginine and ADMA transport - Circulating levels of the cationic amino<br/>acid L-arginine and its endogenously produced homologue asymmetric<br/>dimethylarginine (ADMA) are in delicately poised equilibrium. Dysregulation of<br/>this balance has …
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An Intramural, Tension-modulating Reflex in the Rat Caudal Artery
… nitric oxide (NO) synthesis with N-nitro-L-arginine methyl ester (L-NAME), or the synthesis of cyclic guanosine monophosphate (cGMP) with methylene blue (MB) reduced the EFS-induced relaxation. In addition, inhibition of K<sub>Ca++</sub>-dependent hyperpolarization with tetraethylammonium …
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Structural and Mutational Analyses of Aspergillus fumigatus SidA: A Flavin-Dependent N-hydroxylating Enzyme
… We have also explored the allosteric effect of L-arginine. We provide evidence that an enzyme/coenzyme/L-arginine complex is formed which improves coupling, oxygen reactivity, and reduction in SidA; however more work is needed to fully understand the role of L-arginine as an allosteric effector.
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Biphasic neurogenic vasodilatation in the bovine intraocular long posterior ciliary artery
… be determined. 9.NG-substituted analogues of L-arginine are routinely used to inhibit the NOS family of enzymes. The first of these to be introduced, NG-methyl-L-arginine (L-NMMA), is generally reported to inhibit all three isoforms of NOS. Despite this, however, L-NMMA does not inhibit …
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Cognitive dysfunction studied in animal models of schizophrenia
… with the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME). Furthermore, systemic administration of PCP potentiated latent inhibition in taste aversion conditioning. This effect could be normalized by pretreatment with L-NAME. Finally, acute and sub-chronic inhibition of NO …
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Aktivität und Bedeutung der erythrozytären NOS bei kardiovaskulären Risikofaktoren
… diseases changes in the metabolism of L-arginine-NO cause endothelial dysfunction with reduced bioavailability of NO. Besides endothelial cells, RBC also obtain an active NOS in the vascular system. NO synthesis by RBC-NOS is regulated by similar mechanism and modulates RBC deformability. …
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Functional cell biology and molecular pharmacology of ATP sensitive potassium channels.
… ATP COs typified by pinacidil are sensitive to L-arginine analogues whereas the K ATP COs typified by cromakalim are insensitive to L-arginine analogues. This sensitivity appears to be independent of nitric oxide synthase (NOS) action as the vasorelaxant and Rb efflux responses to pinacidil are …
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Metabolomic Approaches in Parasitology
… family, potentially involved in L-arginine to L-ornithine conversion. Knockout of Tb927.4.1300 resulted in a growth deficit without significant changes in intracellular L-arginine or L-ornithine levels. Recombinantly expressed Tb927.4.1300 failed to catalyze L-ornithine synthesis …
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Dietary Methionine and Lysine Utilization by Chicks as Influenced by Coccidial Infection and Drug Therapy
… the dietary factors were L-lysine$\cdot$HCl, L-arginine, DL-methionine, protein level and source as well as dietary electrolyte balance. Digestibility and bioavailability of crystalline L-lysine$\cdot$HCl were also studied. Coccidial infection was produced via crop intubation of sporulated …
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