Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Kv channels"”.
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Lipid Chemistry and Mechanical State of the Membrane Modulate Ion Channel Function
… focused on voltage-dependent K<sup>+</sup> (Kv) channels. Kv channels serve many different functions in different cells, but most notably underlie action potentials in electrically excitable cells, such as neurons and muscle (Hodgkin and Huxley, 1952, 1945). Kv channel gating is governed by …
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Identification, Characterization and Function of Voltage-Gated and Two-Pore-Domain Potassium Channels in the Mouse Myometrium.
… in outward currents carried by voltage-gated (Kv) and two-pore-domain (K2P) potassium channels are key points of regulation in many excitable cells. Despite these facts little is known about the role of Kv or K2P potassium channels in the regulation of uterine contractility, and certainly …
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Investigating Cerebellar Mechanisms of Schizophrenia by Using a Pharmacological Mouse Model: Regulation of Voltage-Gated Potassium Channels
… and cognition. Voltage-gated potassium (Kv) channels are fundamental to neuronal communication because of their intricate roles in regulating neuronal excitability, thereby governing information processing in the brain. The cerebellum has a significant influence over how this information …
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Potassium channels for high-frequency action potential generation in GABAergic interneurons of Rat Hippocampus
… that allowed me to investigate somatic ion channels under ideal voltage-clamp conditions, I started to examine the functional properties of Kv channels expressed in orien-alveus (OA) interneurons in the hippocampal CA1 region, a major class of dendritic inhibitory interneuron. The main …
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The role of prostaglandins, nitric oxide and oxygen in the ductus arteriosi of the pre-term chicken embryo (Gallus domesticus).
… in mammals and include contributions from ROS, Kv channels, L-type Ca2+ channels, and the Rho kinase pathway. Longer exposure to high oxygen generates increased oxygen induced constriction of the day 19 DA that may be mediated through the Rho kinase pathway.
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The structure of a voltage gated potassium channel
Voltage gated potassium channels (Kv channels) are tetrameric ion channels, responsible for regulating the potassium component of the membrane potential in a large range of cell types ranging from mammalian excitable cells to bacteria. Attempts have been made to elucidate the structure of voltage …
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Regulation of Volume by Spermatozoa and Its Significance for Conservation Biology
… the movement of osmolytes through various channels, including potassium channels. The potassium channels involved in volume regulation of human, monkey, and murine spermatozoa were investigated. Flow cytometry was used to gauge the sensitivity of the volume regulatory process of spermatozoa …
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The Structural and Functional Analysis of a Voltage-Dependent Potassium Channel
<p>Voltage-dependent ion channels are finely tuned to open and allow ion conduction in response to changes in the membrane voltage, a function that lies at the heart of nerve impulse generation and propagation. These channels contain transmembrane voltage-sensing domains that contain highly …
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Hypoxia-induced responses of porcine pulmonary veins.
… hypoxic contraction. This suggested that TASK, KV1.5, BKCa and KATP do not play a role in the mechanism of hypoxic pulmonary venoconstriction however KV channels containing KV2.1 α subunits may modulate the response. Results with L-NAME suggested endothelial dysfunction may not fully account …
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Study of correlation analysis for protein-protein interactions
… analysis on known interacting protein pair, Kv1.2 and β2 subunit. The motif/residue based correlation analysis was successfully verified here. Then we applied this method onto epithelial sodium and chloride channels, which included CFTR and ENaC, Clc2 and ENaC, CACC and CFTR, trying to …
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Characterization of cardiac IKs channel gating using voltage clamp fluorometry
Voltage-gated ion channels make up a superfamily of membrane proteins involved in selectively or non-selectively conducting charged ions, which can carry current in and out of cells, in response to changes in membrane voltage. Currents carried by ion channels influence the voltage across the cell …
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Electrophysiological and morphological analyses in two species of insects, Protophormia terraenovae and Ceratitis capitata
… with specific membrane receptors and/or ion channels located in the apical membrane of taste receptor cells results in the generation of a receptor potential which, in turn, activates the ‘encoder’ region to produce action potentials which propagate to the CNS. This study investigates, in the …