Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Kunitz inhibitor"”.
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QUB-1951: a bioactive peptide from the skin secretion of the Chinese piebald Odorous frog, Odorrana schmackeri
… It was the first time to report a novel kunitz inhibitor peptide discovered from the frog secretion, which provides new insight of unique trypsin inhibitors from natural products.<br/>
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Discovery, structural characterisation and targeted engineering of bioactive peptides from amphibian skin secretion
… QUB-3307 and QUB-2531 exhibited an inhibitory effect on trypsin, which may be due to the presence of a typical Kunitz inhibitor motif, -KCK-, at their C-terminals. However, QUB-1376 failed to retain the inhibitory effect, which indicated that an intact Rana Box domain could …
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Molecular cloning, structural characterisation and functional study of bioactive peptides from amphibian skin secretion
… much attention in the fields of protease inhibitor peptides and antimicrobial peptides. In this study, the skin secretion of two frogs, Amolops hainanensis and Odorrana versabilis, were obtained by use of electrical stimulation. Afterwards, ‘shotgun’ cloning was applied using 3’RACE PCR to …
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Characterisation, bioactivity evaluation and rational modification of bioactive peptides from frog skin secretion and scorpion venom
… In chapter 3 a novel Bowman-Birk type protease inhibitor (ranacyclin-NF) was identified in the skin secretion of Pelophylax nigromaculatus. Besides studying its potential applications, two analogues were designed to study structure-activity relationship of peptide. In Chapter 4, a …