Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Ku protein"”.
-
Functional significance of unique sequences in Mycobaterium smegmatis Ku proteins
Ku is central to the non-homologous end-joining pathway of DNA double strand break repair, first discovered in eukaryotes and more recently in prokaryotes and archaea. This study concerns the importance of two unique sequence features of Ku protein from Mycobacterium smegmatis that include a …
-
Functional Analysis of the Yku Complex in Telomere Length Regulation
The Ku protein from Saccharomyces cerevisiae (Yku) forms, like its human homologue hKu, a heterodimer comprised of a 70kD and an 80 kD subunit. In yeast and mammals, the Ku heterodimer is required for the repair of DNA double strand breaks (DSBs) via nonhomologous end-joining (NHEJ). Interestingly, …
-
Characterization of DNA Binding Activities at Vertebrate Telomeres
<p>Telomere function is carried out by protein factors that either bind directly to telomeric DNA or that are recruited there by DNA binding activities. Thus, telomeric DNA binding activities are central to telomere function. Two types of vertebrate DNA binding activities are characterized in this …