Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Kremen1"”.
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Targeting Kremen1 Downregulation with RVG-9R/siRNA Complexes in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
… which may be linked to synaptic loss seen in AD. Kremen1 (Krm1) is a receptor for Dkk-1. Published and unpublished observations from our laboratory showed that silencing Krm1 with miR-431 can promote regenerative axon growth and prevent synaptic loss in a cell culture model. This study focused on …
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The canonical Wnt signaling pathway affects regeneration of mechanosensory hair cells in Danio Rerio
… Lef1 and a negative regulator of Wnt signaling, Kremen1, were used to study the role of Wnt signaling in regeneration of lateral line hair cells in zebrafish. These Wnt pathway mutant lines show no change in proliferation of supporting cells post injury and shifts in the number of regenerated …