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Showing 1 to 2 of 2 for “"Krabbe's disease"”.

  1. Molecular Mechanisms Involved In Krabbe's Disease

    La leucodistrofia di Krabbe o a cellule globoidi è un disturbo autosomico recessivo a carico del gene codificante per galactosilcerebrosidase (GALC). GALC è coinvolto nel catabolismo di due lipidi molto prodotti nel processo di formazione della guaina mielinica: galactosilceramide e psicosina. A …

    catania Repository record for Molecular Mechanisms Involved In Krabbe's Disease (opens in a new tab)

  2. The Role Of Inflammation In Pathogenesis And Treatment Of Globoid-Cell Leukodystrophy

    Globoid-cell leukodystrophy: GLD, Krabbe's disease) is an autosomal recessive disease caused by a deficiency of the lysosomal enzyme galactosylceramidase: GALC). It results in altered catabolism of the myelin lipid Galactosylceramide. The disease predominantly affects the white matter of the CNS …

    wustl Repository record for The Role Of Inflammation In Pathogenesis And Treatment Of Globoid-Cell Leukodystrophy (opens in a new tab)