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Showing 1 to 20 of 114 for “"Klebsiella pneumoniae"”.
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A Restriction Analysis of Klebsiella Pneumoniae Phage SBS
<p>A Klebsiella phage was isolated from the San Bernardino sewage and its physiochemical properties analyzed. The present study found the density of the phage to be 1.44 g/ml, the burst size to be 10, and the phage had a latent period of 20-25 minutes. The DNA was found to be double stranded and …
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Structural analysis of capsular polysaccharides produced by some emerging Klebsiella pneumoniae serotypes
Klebsiella pneumoniae (K. pneumoniae), a Gram-negative pathogenic bacterium, is a leading cause of neonatal sepsis in low- and middle-income countries (LMICs). Due to rapidly increasing anti-microbial resistance (AMR), it has been ranked among the “critical-priority 1” pathogens to human health by …
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Exploring the Polyclonal Antibody Responses Induced by Klebsiella pneumoniae Derived Outer-Membrane Vesicles
… are Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. Of these, Klebsiella pneumoniae stands out due to its vast genomic diversity with only a small percentage of the genome being dedicated to the core genes, …
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Identification and characterisation of cephalosporins and carbapenem-resistant Klebsiella pneumoniae isolates from Misrata, Libya
… of ESBL and carbapenemase-producing K. pneumoniae isolates from Misrata. Materials and Methods: Two hundred Gram-negative bacillus isolates were collected and identified from hospitals and pathology laboratories in Misrata. Following antimicrobial susceptibility screening, those showing …
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Disentangling bacterial virulence mechanisms: Klebsiella pneumoniae targets post-translational modifications (PTMs) to manipulate innate immunity
Klebsiella pneumoniae is a Gram-negative, multidrug-resistant (MDR) bacteria, causing nosocomial pneumonia, urinary tract infections (UTIs) and sepsis. Klebsiella’s subversion of the host immune response is critical for infection. Therefore, Klebsiella employs a range of novel mechanisms, including …
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Molecular Studies of KpnAI and KpnBI R-M Systems : in KLEBSIELLA PNEUMONIAE M5a1 and GM236
… and <em>Kpn</em>Bl, were recognized in <em>Klebsiella pneumoniae</em> strains M5al and GM236, respectively. In this project, four <em>hsdR</em><sub>KpnAI</sub> clones (pNLA1 to pNLA4) were obtained by using an endonuclease expression-selection method. The <em>hsdR</em><sub>KpnAI</sub> gene …
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Regulation of blaFOX-5b Expression Within Two Different Genetic Backgrounds: Klebsiella pneumoniae and Escherichia coli
Klebsiella pneumoniae and Escherichia coli are major nosocomial pathogens. A clinical isolate of K.pneumoniae and E. coli were found to produce a novel plasmid-encoded ampC P-lactamase gene, blaFOX-5b- These isolates conferred high level resistance to a broad spectrum of antibiotics, including …
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Klebsiella pneumoniae bloodstream infections in hospitalised children at Red Cross War Memorial Children's Hospital : 2006 - 2011
Background: Klebsiella pneumoniae (KP) is a significant paediatric bloodstream pathogen in children. There is little data about KP in South African children. The focus for the present study was to address this knowledge gap. Methods: This study addressed a retrospective case notes review on …
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Epidemiological Typing and Mechanisms of Antibiotic Resistance in Clinically Relevant Klebsiella Pneumoniae Isolated at St. Marina University Hospital – Varna // Епидемиологично типизиране и механизми на антибиотична резистентност в клинично значими Klebsiella pneumoniae, изолирани в УМБАЛ „Света Марина“, Варна
… към бета-лактами и хинолони при клинично значими Klebsiella pneumoniае, изолирани от пациенти, хоспитализирани в УМБАЛ „Света Марина“ - гр. Варна в периода 2014 - 2017г. и да се определи клоналната свързаност на изолатите. Анализът на резултатите, получени в нашите проучвания и сравняването им с …
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The Effect of O Antigen Loss on the Protein Composition and Inflammatory Response Elicited by Klebsiella pneumoniae
Klebsiella pneumoniae is a Gram-negative pathogen associated with numerous infections. Like all Gram-negative bacteria, K. pneumoniae naturally release outer membrane vesicles (OMVs) during all stages of cellular growth. OMVs are composed of the outer membrane components such as lipopolysaccharide …
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Regulation of nitrogen fixation in <i>Klebsiella pneumoniae</i>: The role of Fnr in oxygen signal-transduction
In Klebsiella pneumoniae wird die Aktivität des Transkriptionsaktivators NifA durch NifL in Abhängigkeit von gebundenem Stickstoff und molekularem Sauerstoff geregelt. NifL, ein Flavoprotein, das redox-sensitiv ist, scheint, das Sauerstoffsignal über eine Konformationsänderung auf NifA zu …
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Studying the riboregulatory role of Hfq in Klebsiella pneumoniae using CLASH (crosslinking, ligation and sequencing of hybrids)
… an RBP in a Gram-negative nosocomial pathogen Klebsiella pneumoniae (Kp), using a high-throughput sequencing technique named CLASH (Crosslinking, ligation, and sequencing of hybrids). I performed CLASH in two Kp strains - Ecl8 and Ecl8ΔramR (RamA overexpressor), and established gene regulation …
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Acquisition of an Antibiotic Tolerant Phenotype in Enterobacter cloacae and Klebsiella pneumoniae through Antibiotic-Induced Metabolic Regulation
While Enterobacter cloacae and Klebsiella pneumoniae are part of the normal human microbiota, they are also potential human pathogens and have been associated with the spread of antibiotic resistance. These organisms can enter a physiological state that allows a fraction of each population to …
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Molecular Cloning and Analysis of the Modification Genes of the KpnBl Restriction- Modification System of Klebsiella pneumoniae Strain GM236
… system has been recognized for some time in <em>Klebsiella pneumoniae</em> strain GM236. Previously the restriction subunit (<em>hsdR</em><sub>kpmBI</sub>) was cloned and sequenced, based on the sequence infonnation the <em>Kpn</em>Bl RM system was suspected to be either a type I or type III R-M …
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Regulation of nitrogen fixation in <i>Klebsiella pneumoniae</i>: Nitrogen and oxygen signal perception by the negative regulator NifL
In dem diazotrophen Organismus Klebsiella pneumoniae wird der nif - spezifische Transkriptionsaktivator NifA als Reaktion auf molekularen Sauerstoff und Ammonium durch NifL gehemmt. Die Komplexbildung zwischen NifL und NifA (etwa 1:1-Verhältnis) erfolgt, wenn die Synthese der beiden Proteine in …
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