Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Kir2.1"”.
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The expression of muscarinc acetylcholine receptors on the avian vestibular hair cells and the modulation effects on KIR2.1
… effect on an inward rectifier potassium channel, Kir2.1. Using immunohistochemical, immunocytochemical, and Western blot techniques, we demonstrated for the first time, the expression and co-expression of mAChR subtypes M1-M5 on the peripheral vestibular structures, including hair cells, …
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The Roles of Focal Adhesion Assembly in Membrane Localization of Ion Channels and Action Potential Shape
… inwardly rectifying potassium channels, such as Kir2.1, which set the resting membrane potential to a negative value allowing the activation of depolarizing voltage-gated currents. In the heart, Kir2.1-mediated IK1 current is upregulated during development, but downregulated in certain …
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Molecular mechanisms of neuronal homoeostasis in vivo
… I have used stereotaxic surgery to over express Kir2.1, an inwardly rectifying potassium channel, in vivo in the brains of adult mice. I show that the expression of Kir2.1 through adeno-associated virus (AAV) does not cause any adverse effects in the dentate gyrus nor the CA1 of the mouse …
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Maguk Scaffolds Organize A Key Synaptic Complex In Horizontal Cell Processes Contacting Photoreceptors
… GluR6/7 and inward rectifier potassium channel Kir2.1, closely associated with SAP102 in the processes of invaginating HCs. In contrast, in the mouse retina we identified Chapsyn110 as the major scaffold in the tips of horizontal cells contacting photoreceptors. Kir2.1 was found to be assembled …
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The Role of CREB in Social Isolation and Natural Reward Behavior
… of the inward rectifying potassium channel kir2.1. These studies further the field of depression and anxiety research with a model sensitive to chronic but not acute antidepressant treatment and reveal potential novel mechanisms for the reversal of anxiety-like behaviors.