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Showing 1 to 3 of 3 for “"Kinetic Transition Networks"”.

  1. Anaerobic, NADH-Dependent Haem Breakdown in a Family of Haemoproteins

    … NADH-protein binding sites and to construct kinetic transition networks. From these networks, pathways showing the unfolding and approach of NADH to haem inside the pocket were determined. These pathways highlighted the roles of various residues, thus allowing for a targeted mutagenesis …

    cambridge Repository record for Anaerobic, NADH-Dependent Haem Breakdown in a Family of Haemoproteins (opens in a new tab)

  2. Energy Landscapes for Protein Folding

    … motions and short distances. In this thesis, kinetic transition networks (KTNs) are constructed for various protein folding systems, via approaches based on the potential energy landscape (PEL) framework. By applying geometry optimisation techniques, the PEL is discretised into stationary …

    cambridge Repository record for Energy Landscapes for Protein Folding (opens in a new tab)

  3. Analysing First Passage Time Distributions of Large Ill-Conditioned Energy Landscapes

    … computational tools to investigate the kinetics of competing pathways on multifunnel energy landscapes. Multifunnel landscapes are associated with molecular switches and multifunctional materials, and are expected to exhibit multiple relaxation time scales. Energy landscapes, consisting …

    cambridge Repository record for Analysing First Passage Time Distributions of Large Ill-Conditioned Energy Landscapes (opens in a new tab)