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Showing 1 to 1 of 1 for “"Kinase sirna library screen"”.
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Identification and Characterization of Novel Kinases that Regulate BRCA1 Expression and Function
… form ionizing radiation-induced foci (IRIF), to screen a kinase siRNA library and thirty-two potential positive regulators of BRCA1 were identified. Subsequent validation resulted in fourteen kinases that consistently diminished BRCA1 IRIF. Secondary screening assays for three selected kinases …