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Showing 1 to 3 of 3 for “"Kinase Specificity"”.
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The evolution of protein kinase specificity
… catalysed by a group of enzymes called protein kinases. Through this activity they serve as key regulators of almost all cellular processes. This is achieved at any time by a network of different kinases that are transiently active. The fidelity of cell systems control therefore requires that …
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Structural principles governing kinase specificity towards RNA polymerase II C-terminal domain and their impact on transcription
… phosphorylation. In Chapter 2, I elucidate how kinases can correctly recognize the right residue for phosphorylation. Data presented in this chapter reveals the underlying rules of substrate recognition by CTD kinases which is important for the timely regulation of transcription. Furthermore, in …