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Showing 1 to 2 of 2 for “"Kinase Deoxyribozymes"”.
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Kinase deoxyribozymes
… that is essential for cellular function. Protein kinases, which catalyze phosphorylation, are often motif specific. Engineering these natural kinases to change motif requirements is challenging and often results in decreased substrate specificity. To identify new catalysts for the site-specific …
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Deoxyribozymes for peptide substrates: exploring the landscape of nucleophiles and electrophiles
… catalyze various bioorganic reactions are called deoxyribozymes. Deoxyribozymes do not occur naturally and are identified using a combinatorial chemistry technique called in vitro selection. Since the discovery of the first artificial deoxyribozyme that catalyzes cleavage of phosphodiester bonds …