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Showing 1 to 1 of 1 for “"Kidneys -- Diseases -- Animal models."”.
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Role of T cells and cytokines in the induction of tolerance to renal tubular antigen in active Heymann nephritis
… to end-stage kidney disease. The best available animal model of MN is active Heymann nephritis (HN) in which rats are immunized with renal tubular antigen (RTA) in complete Freund's adjuvant (CFA). Rats develop heavy proteinuria, a key measure of glomerular damage, and the disease is …