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Showing 1 to 15 of 15 for “"Kidney Tubules"”.
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Senescent Changes in the Kidney of the Yellow Mud Turtle Kinosternon flavescens
… addresses age-related changes that occur in the kidneys of reptiles and compares them to senescent changes in mammalian kidneys. Kidney sections from a wild population of turtles ranging in age from 6 to 35 years were examined histologically by light and electron microscope. Kidney tubules of the …
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The Role of Daam1 In Kidney Development
<p>Kidneys, like most organs in our bodies, consist of a network of epithelial tubules. Kidney tubules are called nephrons, and their morphology is important for kidney function. Nephrons develop from mesodermally derived aggregates of progenitor cells. The nephric progenitors organize into nephric …
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The Role of Daam1 In Kidney Development
<p>Kidneys, like most organs in our bodies, consist of a network of epithelial tubules. Kidney tubules are called nephrons, and their morphology is important for kidney function. Nephrons develop from mesodermally derived aggregates of progenitor cells. The nephric progenitors organize into nephric …
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Epithelial Tubular Fusion, Measuring Interconnection, and the Quest for Solving the Continuity Problem
The formation of functional epithelial tubules is a central feature of many organ systems. Although it has been well-studied how epithelial cells form tubules, it is not well understood how tubules and related epithelial micro-tissues such as spheroids and organoids interconnect with each other to …
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Mutation of Polaris, an Intraflagellar Transport Protein, Shortens Neuronal Cilia
… cilia are non-motile organelles having 9+0 microtubules that project from the basal body of the cell. While the main purpose of motile cilia in mammalian cells is to move fluid or mucus over the cell surface, the purpose of primary cilia has remained elusive for the most part. Primary cilia are …
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Leveraging cellular models of polycystic kidney disease for mechanistic discovery and therapeutic development
Polycystic kidney disease (PKD) is a life-threatening disorder characterized by the progressive expansion of fluid-filled cysts originating from kidney tubules. As the leading monogenic cause of renal failure, PKD affects 1 in ~1,000 people with 50% of patients meeting criteria for end-stage renal …
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Molecular and Functional Analyses of Transport Proteins for Organic Anions
… in the CP are similar to those in the kidney. Therefore, I performed comparative experiments with model organic anions in isolated proximal kidney tubules of killfish and CP of rat and spiny dogfish shark. ·First, I studied transport of the fluorescent cAMP analog fluo-cAMP. Inhibition …
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Functional and pathological responses of selected aquatic organisms to chrysotile asbestos
… for 30 days accumulated up to 390 fibers/mg in kidney tissue. Egg and larval Medaka were exposed to 0-10¹⁰ fibers/liter of chrysotile until hatching and for thirteen weeks, respectively. Eggs responded erratically to asbestos exposure and no conclusive trends could be drawn. Larval Medaka …
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Physiological effects of feeding high magnesium levels to steers
… intestine. The Mg concentration in the liver, kidney, skeletal muscle and rib-bone and the P concentration in the skeletal muscle increased linearly (P<.05) with dietary Mg. Histologically, amorphous crystals were seen in the kidney tubules of all animals. Increasing dietary Mg in the steers …
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Tubular factors as the causes of reduced kidney function during ischemic renal failure in rats
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Development of Therapies to Treat Polycystic Kidney Disease
Polycystic kidney diseases (PKD) are genetic disorders characterized by fluid filled cysts in the kidney tubules and liver bile ducts. There are two forms of PKD, autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). The focus of the studies …
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In vivo renal synthesis and renal tubular secretion of para-tyramine in the rabbit
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Characterizing Renal Interstitial Heterogeneity and Its Role in Nephron Patterning
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Investigating the functionality of African-specific variants in the TGFB1 regulatory region and their potential role in HIV-associated kidney complications
… n=3). Compared to the HIV-positive controls the kidney tubules of HIVAN biopsies had higher H-scores. Strikingly, the interstitium of HIVAN samples stained much more prominently (17/18) than both control groups suggesting that TGF-β1 staining in the renal interstitium appear to be specific for …
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Role of angiotensin in the vascular response to chronic renal tubular obstruction
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).