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Showing 1 to 1 of 1 for “"Kidney Diseases, Cystic"”.
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Sumo and Ubiquitin Ligases Regulate Hepatocyte Nuclear Factor - 1 Beta Transcriptional Activity
… regulates tissue-specific gene expression in the kidney, liver, and other organs. Humans with heterozygous mutations of HNF-1β develop maturity-onset diabetes of the young type 5 (MODY5) associated with cystic abnormalities of the kidney. A yeast two-hybrid screen was performed to identify …