Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1448 for “"Kidney"”.
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Targeting Glutamine Metabolism in Kidney Development and Polycystic Kidney Disease
Polycystic kidney disease is a hereditary disorder characterized by the progressive manifestation of numerous fluid-filled sacs, known as cysts, within the renal epithelia. The enlargement of the cysts causes the gradual replacement of normal kidney parenchyma which leads to impairment of renal …
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Chemoprevention in Kidney Cancer
… studies that explore the role of statins in kidney cancer. Furthermore, I evaluate the potential for different interpretations from the same data depending on the method of classifying medication use. Methods: The first study was a population-based case-control study evaluating the …
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Engineering Complex Kidney Structures for Disease Modelling, Drug Testing, and Studying Kidney Development
Although existing kidney tissue engineering systems and cell-based strategies favoured significant advances in the field, they cannot reproduce the organ’s complex architecture. This prevented the use of these tissues in studying kidney development realistically, modelling diseases, and …
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Kidney tissue characterization using magnetic resonance in HIV infected individuals undergoing kidney biopsy
BACKGROUND: Kidney disease is a common complication of human immunodeficiency virus (HIV) infection. Kidney biopsy is the gold standard for assessing causation, but being invasive, it carries increased risk in advanced chronic kidney disease (CKD). Magnetic resonance imaging (MRI) is noninvasive …
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Mitochondrial Metabolism of Human Kidney Cancers
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Economic studies of chronic kidney disease
… 9% of the global population has chronic kidney disease (CKD). Patients with end-stage renal disease (ESRD), the most advanced form of CKD, comprise 0.15% of the global population but consume 2-4% healthcare budgets. While the impact of CKD and ESRD are experienced most immediately by …
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Dietary phosphorus in chronic kidney disease
… is common in the later stages of chronic kidney disease and is a universal problem in end stage kidney disease, where it is associated with increased morbidity and mortality. Treatment includes a low phosphorus diet, that imposes numerous dietary restrictions, lacks a robust evidence base …
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Improvements to the kidney dialysis machine
Five changes were suggested to improve the kidney dialysis machine, including a conductivity control feedback system, a positive pressure deaeration system, a balancing system for dialysate flow control, a diaphragm-type blood pump, and an ultrafiltration control system using blood pressure …
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Association of GLP-1 Receptor Agonist Use with Kidney and Cardiovascular Outcomes in Stable Kidney Transplant Recipients
… in reducing cardiovascular events and improving kidney function in patients with type 2 diabetes. Due to these hopeful improvements, kidney transplant recipients (KTRs) have started using GLP-1RA. However, their effects in KTRs remain largely unstudied in clinical studies. This thesis uses a …
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The Localization of β-catenin During Xenopus Kidney Development: A Look into β-catenin's Role in Kidney Development
… localization in the developing pronephric kidney in real-time. Future studies will determine how inhibitory/overexpression factors influence β-catenin localization in the pronephros. These studies will facilitate a deeper understanding of the canonical pathway in organogenesis.</p>
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Simple Tests for Assessing Kidney and Cardiovascular Function in Chromic Kidney Disease Patients (Stages 2, 3 and 4)
… making and forms the basis of classification for kidney function. Moreover the interpretation of risk factors for progression of CKD linked to cardiovascular disease (CVD) remains difficult, particularly in older subjects. To address this GFR and the cardiovascular parameters arterial stiffness, …
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The Role of Daam1 In Kidney Development
<p>Kidneys, like most organs in our bodies, consist of a network of epithelial tubules. Kidney tubules are called nephrons, and their morphology is important for kidney function. Nephrons develop from mesodermally derived aggregates of progenitor cells. The nephric progenitors organize into nephric …
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The Role of Daam1 In Kidney Development
<p>Kidneys, like most organs in our bodies, consist of a network of epithelial tubules. Kidney tubules are called nephrons, and their morphology is important for kidney function. Nephrons develop from mesodermally derived aggregates of progenitor cells. The nephric progenitors organize into nephric …
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Molecular diagnosis in inherited polycystic kidney disease
Polycystic Kidney Disease (PKD) incorporates a number of genetically but not always phenotypically distinct inherited cystic kidney disorders. Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most frequent, with an estimated prevalence of 1:1000. Though common, there are numerous …
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