Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 62 for “"Ki67"”.
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The Columnar Lined Esophagus: aspects on the assessment of dysplasia and on the relationship with the esophageal submucosal glands
… for immunohistochemical assessment of p53 and Ki67 as surrogate dysplasia markers. Using these methods, the inter-observer agreement improved substantially from mean k value 0.24 for H&E evaluation to 0.71 and 0.52 for p53 and Ki67 evaluations, respectively. There was a correlation between …
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Obesity and Aggressive Prostate Cancer: Bias and Biology
… I receptor (IGF-IR), and proliferation marker Ki67, in 357 cases who received a RP. We then tested for associations between patient history of obesity and other demographic and clinical characteristics. Expression of AR and Ki67 were positively associated with tumor grade and stage, while Ki67 …
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Etablierung und Validierung eines Gewebemicroarrays für Non-Hodgkin-Lymphome
… der Maximalexpression des Proliferationsmarkers Ki67 untersucht. Ferner wurden ein Vergleich von verschiedenen Markern zwischen Frischmaterial und formalinfixiertem Paraffinmaterial erstellt, sowie ein Immunphänotyp für ausgewählte NHL Enitäten.
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The role of EGFR, HER 2-4, heregulin and downstream signalling in prostate adenocarcinoma
… Methods Immunohistochemical staining for HRG, KI67 (proliferation), TUNEL (apoptosis) was performed on pilot study specimens. Further IHC for EGFR, HER2, HER3, HER4, HRG, KI67 and TUNEL was performed on HSPC tissue microarrays. Correlations between target protein expression and the outcomes …
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Effects of varying energy intakes on mammary growth and development in prepubertal heifers
… revealed estrogen receptor (ER) and Ki67 (nuclear proliferation antigen) positive cells, type IV collagen, fibronectin (FN), and laminin. Images representing 4 increasing grades were used to quantify ECM protein deposition. Lumenal and stromal areas were 3.5 ± 1.4% higher (p<0.01) and …
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Μελέτη της ακτινικής δερματίτιδας σε ασθενείς με καρκίνο μαστού : συσχέτιση με κλινικές και παθολογοανατομικές παραμέτρους
… που σχετίζονται με την ανάπτυξη του όγκου (Ki67, ATM) και των πρωτεϊνών που επηρεάζουν την οξειδωτική κατάσταση και τον μεταβολισμό του κυττάρου (HIF-1a, Inos, aGluc), φάνηκε ότι πιθανώς συμβάλλουν στον κίνδυνο εμφάνισης ακτινικής δερματίτιδας. Συμπεράσματα: παρότι η ιστοπαθολογική ανάλυση …
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Colony Stimulating Factor-1 Receptor (CSF-1R) Expression, Degradation, and Signaling in Lipid-Laden Macrophages
… and quantify CSF-1R, pAkt, pERK, pCSF-1R, and Ki67. To synchronize the signaling process, macrophages were deprived of CSF-1 supplemented media before experiments. The lipid-laden macrophages had a decreased rate of CSF-1R expression. The degradation of CSF-1R was unchanged after the initial …
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Expresión de fascina-1 y Topoisomerasa 2 alfa en el carcinoma de mama: correlación con los subtipos histológicos y otros marcadores pronósticos
… de Nottingham) y resultados de estudios IHQ: Ki67, p53, BCL2, receptor de estrógeno (RE) y progesterona (RP). Además, se lleva a cabo una determinación IHQ adicional de FSCN1 (55k-2; Agilent Dako, Santa Clara, CA, EE. UU.) cuantificada por un método semicuantitativo que evalúa tanto el grado …
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Characterization of CD8 T cell responses in Mycobacterium Tuberculosis infection
… in CD8 T cells from TB and LTBI donors. Bcl-2, Ki67,CD95, CD57, CD127 and IFNγ were thus measured in each group.
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The structural and functional changes of blood vessels during aging
… and fibronectin, and the proliferation marker Ki67 showed strong adventitial origin. The changes observed in the vascular adventitia with aging clearly demonstrate an important role in the process of vascular aging.
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“Valutazione dell’incidenza delle recidive locali ascellari in pazienti operate per cancro della mammella con micro metastasi del linfonodo sentinella: associazione con il pattern immuno-istochimico”
… di estrogeni e progesterone, HER2 negativo, Ki67 negativo) e un altro i tumori con assetto luminale (luminal A e luminal B). Valuteremo quindi se ci sarà una significativa differenza tra i due gruppi presi in considerazione tale da valutare l’ipotesi di modificare l’approccio chirurgico al …
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Angiotensin-(1-7) Reduces Prostate Cancer Growth and Metastasis by Altering the Tumor Microenvironment
… treated with Ang-(1-7) had a 78% reduction in Ki67 and a 55% decrease in the phosphorylation of the MAP kinases ERK1 and ERK2, compared to tumor tissue from Ang-(1-7)-medicated animals, suggesting that the heptapeptide reduces cell proliferation. A significant reduction in both LNCaP and PC3 …
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Characterisation of mucosal tissue in the foreskin after voluntary medical male circumcision
… MMC; b) investigate the number of Langerhans, Ki67+ and CD4+ T cells in the inner and outer foreskin and c) identify the impact of asymptomatic STIs on the numbers and proliferative capacity of foreskin-resident Langerhans and CD4+ T cells.
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Perfil inmunohistoquímico de los adenocarcinomas nasosinusales de tipo intestinal y lesiones premalignas
… ¿-catenina, EGFR, HER2-neu, p53, p16, ki67, COX2, TNF¿, p65 e iNOS. Estudio de los cambios histológicos observados en tejido sano adyacente al tejido tumoral y de fosa nasal contralateral y estudio IHQ a este nivel. RESULTADOS: El 97% de los pacientes eran hombres con una media de edad …
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Suppression of Carcinogenesis and Tumor Progression by an Energy Restriction-Mimetic Agent in Murine Models of Prostate Cancer
… lesions, as determined by immunostaining for Ki67 and western blotting for PCNA. OSU-CG5 also decreased the levels of the AR, phosphorylated Akt (p-Akt), and IGF-1R within the prostates of these mice. When 6-week-old, intact, male TRAMP mice were fed an AIN-76A diet containing 1286 ppm of …
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Behaviour of human myoblasts in vitro: role of ageing and inflammatory cytokines
… proliferating muscle cells were desmin, NCAM and Ki67, and markers of differentiating muscle cells were myogenin and myosin heavy chain. Additional parameters observed were DNA damage and analysis of specific cytokines in the cell secretome. No differences in any parameter measured were found …
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Heterogeneity in vascular smooth muscle cell gene expression and its association with clonal proliferation in models of vascular disease
… expression of Sca1 and proliferation marker Ki67. Moreover, Ki67+Sca1+ VSMCs were identified post-CL via flow cytometry, indicating that Sca1+ VSMCs indeed expand in disease. Investigation of candidate genes with differential expression across this pseudotime revealed enrichment for VSMC …
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Melanocyte proliferation in wounded skin in vitro: a histological and immunohistochemical analysis
… staining using the proliferation marker, Ki67, was used. Results show that after an initial lag phase, with no detectable cell proliferation at the wound edges, dividing keratinocytes were seen at day two post-wounding. The number of dividing keratinocytes peaked at day five, where after …
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Yap1 Expression Predicts Sensitivity to Dual Akt/P70S6K Inhibition In Ovarian and Uterine Malignancies
… (Hec1a) cancer and reduced proliferation (Ki67) and angiogenesis (CD31) indices and increased cell death (cleaved caspase-3) markers. Synergy between MSC2363318A and paclitaxel was observed <em>in vitro </em>in protected (IC50 ≥ 5 µM) cell lines. RPPA identified YAP1 as a candidate marker …
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Novel Effects of Simvastatin on Uterine Fibroids
… the expression of the proliferation marker Ki67 in xenograft tumor tissue as examined by immunohistochemistry. In conclusion, simvastatin can be a promising treatment for uterine fibroid. Further studies, including pharmacokinetic and drug delivery studies, are required.
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