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Showing 1 to 3 of 3 for “"Ketone Body metabolism"”.
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Cardiomyocyte-Specific Deficiency of Ketone Body Metabolism Promotes Accelerated Pathological Remodeling
… indicate that altered substrate and energy metabolism can cause cardiomyopathy. Therefore, deeper understanding and, ultimately, judicious nutritional and pharmacological manipulation of myocardial metabolism are expected to improve morbidity and mortality attributable to heart failure. …
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The role of pyruvate dehydrogenase kinase in glucose and ketone body metabolism
… Low oxaloacetate resulted in overproduction of ketone bodies by the liver and inhibition of ketone body and fatty acid oxidation by peripheral tissues, culminating in ketoacidosis and hypothermia. Furthermore, when fed a ketogenic diet consisting of low carbohydrate and high fat, DKO mice also …