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Showing 1 to 16 of 16 for “"Ketone Bodies"”.
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Hepatic acetogenesis and ketogenesis in neonatal swine
Reports of low circulating ketone bodies ($\beta$-hydroxybutyrate, $\beta$-OHB & acetoacetate) in suckling piglets and evidence of minimal hepatic ketone body production from fatty acids in vitro suggested that, unlike previously-studied neonates, enhanced ketogenesis does not characterize the …
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Cardiomyocyte-Specific Deficiency of Ketone Body Metabolism Promotes Accelerated Pathological Remodeling
… have been explored extensively, the influence of ketone bodies, which are highly competitive substrates for myocardial oxidative metabolism, remains ill-defined, in part due to their low circulating concentrations in fed states. Here I illuminate the roles of myocardial ketone body metabolism …
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Carnitine and Altered Lipid Metabolism in Iron-Deficient Rats Pre- and Postweaning (Ketogenesis)
… fatty acids into mitochondria for oxidation and ketone production. Ketone bodies are a major energy source for suckling animals.
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Comparison of Weight Reduction of Human Subjects Fed 1300 Calorie, Lacto-Ovo-Vegetarian Diets with Two Levels of Carbohydrate
… periods. Weight loss, satiety value, urinary ketone levels, as well as changes in glucose tolerance, serum insulin, cholesterol, free fatty acid, and uric acid levels were compared. Total weight loss averaged 12.9 pounds in the 30 per cent carbohydrate group and 13.6 pounds in the 50 per cent …
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The role of mammalian target of rapamycin complex 1 in hepatic physiology and disease
… shifts to fatty acid catabolism and generates ketone bodies to supplement lowered glucose levels. We find that constitutive activation of mTORC1 prevents the liver from initiating fatty-acid oxidation and ketone production in response to fasting. Many aspects of the hepatic fasting response …
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EVALUATING THE EFFECTS OF FASTING CONDITIONS IN COMBINATION WITH TEMOZOLOMIDE FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME
… lowers systemic glucose levels and elevates ketone bodies like ß-hydroxybutyrate (ß-HB). This study sought to evaluate the effects of fasting in combination with TMZ on viability of GBM cell lines LN229 and T98G, and normal astroglial cell line SVG p12. Glucose restriction significantly …
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Effect of dry period diets varying in energy density on health and performance of periparturient dairy cows: a study of dry matter intake, lactation performance, fertility, blood parameters and liver condition
… did not significantly affect ovarian activity, ketone bodies in milk as estimated by Ketolac test or liver fat infiltration. Glucose concentration in blood increased significantly with increased energy level, there was also a significant effect of periods and parity. Treatment did not affect BHB …
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Energy levels and anaerobic endproducts in the brains of two species of teleost fish at death in anoxic water
… and glycogen with no change noted for glucose, ketone bodies (betaâ hydroxybutyrate and acetoacetate), or alternative anaerobic endproducts (succinate, alanine, propionate, isobutyrate, isovalerate, and ethanol). Lactic acid increased two-fold with anoxia. The bullhead was able to generate ATP …
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Toxicity and biotransformation of 1,1,1,3,3-Pentafluoropropane, 3,3,3-Trifluoropropionic acid and 1,1,1,3-Tetrachloropropane
… In addition, the observed high level of ketone bodies might have been responsible for life-threatening possible ketoacidosis. In general, ketoacidosis occurs after an imbalance between glycolysis, lipolysis, TCA cycle activity and respiratory function. Based on the results, ß-oxidation of …
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The role of pyruvate dehydrogenase kinase in glucose and ketone body metabolism
… Low oxaloacetate resulted in overproduction of ketone bodies by the liver and inhibition of ketone body and fatty acid oxidation by peripheral tissues, culminating in ketoacidosis and hypothermia. Furthermore, when fed a ketogenic diet consisting of low carbohydrate and high fat, DKO mice also …
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Metabolism in vivo of 1, 3-butanediol in the rat
… activity in the urine. A considerable amount of ketone bodies was detected in urine of rats after feeding BD while no detectable ketone bodies were found in the urine of control rats. In addition, relative specific activities of urinary BD and S -hydroxybutyrate were 0.91 and 0.50 respectively. …
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L-Carnitine Supplementation for Periparturient Dairy Cows
… of palmitate to acid-soluble products (ketone bodies) on d 2 but not on d 10. Accordingly, plasma beta-hydroxybutyrate concentrations were elevated in the 50 and 100 g/d treatments in the first 2 wk of lactation. Carnitine supplementation decreased liver triglyceride, increased liver …
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Morphological and functional study of cerebral aging in rat
… regimen (the change forces the brain to use ketone bodies (KB) in alternative to glucose to satisfy the energetic needs) and B) a behavioural task able to induce the formation of inhibitory avoidance memory. A) Fifteen male Wistar rats of 19 months of age were divided into three groups …
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Metabolic Regulation by Fibroblast Growth Factor 21
… genetic program whereby lipids are converted to ketone bodies through a process known as ketogenesis. Here, I show the effects of FGF21 as a fasting hormone that is expressed in liver and contributes to the regulation of adipose tissue and hepatic ketogenesis during the fasted state. Using in …
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Feasibility of a Dietary Intervention Using Coconut Oil on Cognition and Quality of Life in Older Adults: Randomised Controlled Pilot study.
… (MCTs) and ketogenic diets as a source of ketone bodies to improve cognitive functions in older adults with MCI or Alzheimer’s disease. However, the current study relies on the consumption of the whole food component (coconut oil) that is rich in medium chain fatty acids, to induce ketosis. …
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The effect of overfeeding and obesity on canine adipose tissue and skeletal muscle transcriptomes
… focal adhesion, synthesis and degradation of ketone bodies and amino sugar metabolism. This study demonstrates that there are a core set of genes that differentiate adipose tissue depots regardless of obesity status, that may underlie differences in depot metabolism and inflammation. Skeletal …