Global ETD Search
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Showing 1 to 3 of 3 for “"Keratin genes"”.
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Identification of genetic variation in the Keratin-associated protein and KRT33A genes of the Swakara sheep of Namibia
Keratins are structural intermediate filamentous proteins that constitute about 90% of the total wool fiber in sheep. The protein gene family is divided into two groups which are the Keratin Intermediate-Filament proteins (KRTs) and the Keratin-Associated proteins (KAPs). The KRTs form the skeletal …
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Mechanisms of epigenetic regulation in epidermal keratinocytes during skin development. Role of p63 transcription factor in the establishment of lineage-specific gene expression programs in keratinocytes via regulation of nuclear envelope-associated genes and Polycomb chromatin remodelling factors.
… Here we show that in p63-null mice about 32% of keratinocytes showed altered nuclear morphology. Alterations in the nuclear shape were accompanied by decreased expression of nuclear lamins (Lamin A/C and Lamin B1), proteins of the LINC complex (Sun-1, nesprin-2/3) and Plectin. Plectin links …
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Exploring Molecular Mechanisms Controlling Skin Homeostasis and Hair Growth. MicroRNAs in Hair-cycle-Dependent Gene Regulation, Hair Growth and Associated Tissue Remodelling.
… and altered differentiation of hair matrix keratinocytes and hair shaft formation. Microarray, qRT-PCR and Western blot analyses revealed that miR-31 negatively regulates expression of Fgf10, the components of Wnt and BMP signalling pathways Sclerostin and BAMBI, and Dlx3 transcription …