Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"Karyotypes"”.
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Dentofacial morphology in Turner Syndrome karyotypes
… differing from controls compared to other karyotypes. Also for the dentoalveolar arch morphology the 45,X/46,XX group had fewer variables differing from healthy females. The isochromosome TS group exhibited the smallest dental crown width for several teeth, while 45,X/46,XX hade the largest …
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Karyotypes and Case Studies of 17 Down's Syndrome Individuals
… blood. At least 30-50 cells were counted and karyotypes made for each patient. Findings. The cell counts and karyotypic studies verified the presumption that 16 patients had mosaic Down's syndrome and that one patient had translocation Down's syndrome. The chromosome counts showing 46 …
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Karyotypes and Case Studies of Ten Individuals With Suspected Sex Chromosome Anomalies
… Chromosomes were counted in 30-50 cells and karyotypes prepared with emphasis on identifying the X-chromosome complement of each cell line. Case studies of the family history and physical features of each individual were done. Findings. Six female residents suspected of having a 45,XO …
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Evaluation of maternal serum triple screen as an identifier of trisomy 21 pregnancy
… age were reviewed. The percentages of abnormal karyotypes in the two populations were not significantly different from each other or the expected value. While 3% of all cases with normal karyotype had an abnormal ultrasound, 33% of cases with abnormal karyotypes had an abnormal ultrasound. This …
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Chromosomal inversions as a mechanism for sympatric differentiation in common quails
… spans about 12% of the genome and defines three karyotypes (AA, AB, BB) that differ in morphology and migratory behaviour while still coexisting and interbreeding in parts of the western Palearctic. This thesis assess how this rearrangement shapes population processes and contributes to …
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Fusion genes in breast cancer
… cancers often have complex, highly rearranged karyotypes which have proved difficult to analyse using classical cytogenetic techniques. The aim of this project was to search for fusion genes in breast cancer by using high-resolution mapping of chromosome rearrangements in breast cancer cell …
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Studies of the efficacy of Ribonucleotide Reductase inhibition in preclinical models of Acute Myeloid Leukemia in combination with standard and novel therapeutics
… are multiple reasons for this, including complex karyotypes in elderly patients, other comorbidities, and chemoresistance. This group of patients needs more effective chemotherapeutic options.
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Biochemical investigations of the evolution and systematics of certain pocket mice (Rodentia: Heteromyidae)
… On the basis of differences in morphology, karyotypes and allozymes between the subspecies of Chaetodipus penicillatus, others have suggested that this taxon may include cryptic species. The subspecies C. p. penicillatus and C. p. pricei were examined here.
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MOLECULAR MECHANISMS ORCHESTRATING LYSOSOME-MEDIATED DEGRADATION OF RIBOSOMES IN ANEUPLOID CELLS
… of aneuploid daughter cells with unbalanced karyotypes. This condition has a profound impact on cell physiology, causing a plethora of cellular stresses. One of the most prominent effects of abnormal karyotypes is the development of proteotoxic stress, which is characterised by the …
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Variação morfométrica e citogenética em Kerodon rupestris (Wied, 1820) (Rodentia: Caviidae)
… of K. rupestris. The morphological and karyotypes evidences suggest that: a) a significant geographical variation takes place; b) morphologically, the sub-fossils specimens present cranial medium values larger than the recent individuals at the same age; c) a clinal increment variation …
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A Mechanistic Evaluation of the Role of Aneuploidy During Oncogenesis
… untransformed cells harboring highly complex karyotypes trigger a natural killer cell-mediated immune response. We find that activation of the NF-κB pathway is responsible for such aneuploidy-associated immune clearance in vitro. We also provide evidence that potential mutations may counteract …
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Tracking profiles of genomic instability in spontaneous transformation and tumorigenesis
… that facilitates the generation of many unique karyotypes within a cell population. Considering cancer cell populations to be complex-adaptive systems, multi-level analyses were performed longitudinally including whole genome microarray, population karyotype analysis, and determination of cell …
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Karyotype polymorphism in indigeneous goats from two Zambian provinces
… goats in these two provinces revealed similar karyotypes, indicating that they are likely to be related. There were no aberrations observed. Due to small sample size, this study is not a definitive study; therefore, further research should be conducted to verify the chromatin band resemblances …
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Karyotype polymorphism in indigeneous goats from two Zambian provinces
… goats in these two provinces revealed similar karyotypes, indicating that they are likely to be related. There were no aberrations observed. Due to small sample size, this study is not a definitive study; therefore, further research should be conducted to verify the chromatin band resemblances …
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A chromosomal analysis of 25-day pig embryos
… cultures and a comparison was made between karyotypes prepared from the dam with those prepared from her 25-day embryos. The mean ovulation rate of the nine gilts was 11.8 ± 0.4. A total of 75 embryos were recovered, of which six were degenerating. In addition to the regressing embryos, …
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Contribuição à citotaxonomia dos Scorpaeniformes (Osteichthyes - Teleostei): estudos citogenéticos em espécies do litoral do Rio de Janeiro, Brasil
… the cytotaxonomy and phylogeny of the order. The karyotypes of the Scorpaenidae species analyzed in this study confirm the great chromosome diversity found in the family in previous studies. Thus far, the karyotype of P. punctatus is unique in the arder and is hypothesized to have been originated …
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Chromosome identification and analysis in selected lines of laboratory mice
… of the two treatments, trypsin and no trypsin. Karyotypes for each line were made with no chromosomal abnormalities detected in any of the lines. The selection regime followed has produced significant genetic change in several characteristics of these mice. However, these changes have apparently …
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Chromosomal complements and variation in some Venezuelan annual killifishes (cyprinodontidae)
Karyotypes of nine species of Venezuelan annual killifishes were compared. Karyotypic differences were found between species and between some genera. A chromosomal sexual dimorphism was found in <u>Pterolebias hoignei</u> (2N = 46). Males of this species possess a single large "Y" chromosome. No …
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Mechanisms and Consequences of Chromosomal Instability in Malignant tumours
… chromosomal instability is associated with karyotypes with extensive structural chromosomal rearrangements. By applying a combination of subtelomeric FISH, G-banding and multicolour FISH, a high resolution for cytogenetic analysis of tumours with chromosomal instability could be obtained. …
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